w Antibody

1. Using a transgenic lines, we show that the Fab-7 insulator of the bithorax complex and the MDG4 (gypsy) insulator are able to disrupt weak transcription derived from the enhancer regulating the white gene expression in the eyes. PMID: 29372797
2. data suggest that a White-cGMP interaction modulates the timing of locomotor recovery from anoxia PMID: 28060942
3. Data suggest that age-dependent behavioral/physiological changes differ between wide-type flies (Canton-S flies) and genetically engineered flies null mutation of white gene (w1118 flies); old w1118 flies exhibit decreased path length per minute and reduced 0.2 s path increment compared with young flies, whereas old Canton-S flies exhibit same path length per minute and same 0.2 s path increment compared with young flies. PMID: 28087331
4. White modulates the timing of locomotor recovery from anoxia. PMID: 27029736
5. this study we have used the CRISPR/Cas9 system to introduce site-specific mutations in the D. suzukii white (w) and Sex lethal (Sxl) genes. PMID: 26721433
6. Genetic analysis with a series of crosses revealed that the White gene was not associated with the phenotype of boundary preference in wildtype flies. PMID: 26351842
7. it was observed that Mod(mdg4)-67.2, a component of the gypsy insulator, interacted with the Zeste protein, which is critical for the eye enhancer-white promoter communication. PMID: 23861668
8. Using genetics and pharmacology, we identified the metabolite transporter White and white-dependent serotonin as suppressors of phototactic personality PMID: 23150588
9. H3K9me2 levels at the white gene directly correlate with its level of expression. PMID: 22634714
10. Data show that maize B1 transgenic lines exhibit cis-silencing of white gene but epigenetic activation of white gene expression in trans. PMID: 22729404
11. This allele enhances mutations in the subset of other eye-color genes with phenotypes similar to garnet. PMID: 11962627
12. The promoter and enhancer region of white gene was studied. PMID: 16480133
13. An insulator element is almost contiguous to the white 3'UTR. PMID: 18086699
14. Assay of cGMP transport in w(-) (mutant) tubules shows that w is required for cGMP transport but not cAMP transport. Targeted over-expression of w in w(-) tubule principal cells significantly increases cGMP transport compared with that in w(-) controls. PMID: 18310115

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KEGG: dme:Dmel_CG2759

STRING: 7227.FBpp0070468

UniGene: Dm.19661