XRCC1 Antibody

Code CSB-PA295370XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) XRCC1 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
XRCC1 antibody; At1g80420 antibody; T21F11.25 antibody; DNA-repair protein XRCC1 antibody; AtXRCC1 antibody; Homolog of X-ray repair cross complementing 1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana XRCC1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Involved in DNA demethylation pathway by stimulating cytosine methylation (5-meC) excision, gap tailoring, and DNA ligation.
Gene References into Functions
  1. XRCC1 is a component of plant base excision repair and functions at several stages during active DNA demethylation in Arabidopsis PMID: 23316050
  2. established existence of a Ku-independent, Xrcc1-dependent double-strand breakage repair pathway PMID: 21070408
Subcellular Location
Nucleus.
Database Links

KEGG: ath:AT1G80420

STRING: 3702.AT1G80420.1

UniGene: At.10181

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