XRN2 Antibody

Code CSB-PA875525XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) XRN2 Polyclonal antibody
Uniprot No.
Target Names
XRN2
Alternative Names
XRN2 antibody; At5g42540/At5g42550 antibody; K16E1.1/K16E1.2 antibody; 5'-3' exoribonuclease 2 antibody; AtXRN2 antibody; EC 3.1.13.- antibody; Protein EXORIBONUCLEASE 2 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana XRN2 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Possesses 5'->3' exoribonuclease activity. Acts as an endogenous post-transcriptional gene silencing (PTGS) suppressor. Degrades miRNA-derived loops, excised during miRNA maturation in the nucleus. Involved in pre-rRNA processing. Involved in the primary exonucleolytic shortening of the 5' external transcribed spacer (5'ETS), required for endonucleolytic processing at site P by the U3 snoRNP complex. Involved with XRN3 in the 5'-end processing of 5.8S and 25S rRNAs. Contributes with XRN3 to polyadenylation-dependent nuclear RNA surveillance. Involved in the degradation of aberrant polyadenylated pre-rRNA through 5'-end processing.
Gene References into Functions
  1. AtXRN2 has a role in ribosomal RNA processing. PMID: 20338880
  2. The nuclear exoribonucleases XRN2 and XRN3 the nucleotidase/phosphatase FIERY1 are endogenous posttranscriptional gene silencing suppressors. PMID: 17993620
Subcellular Location
Nucleus.
Protein Families
5'-3' exonuclease family, XRN2/RAT1 subfamily
Tissue Specificity
Expressed in roots, leaves, stems and flowers.
Database Links

KEGG: ath:AT5G42540

STRING: 3702.AT5G42540.2

UniGene: At.16936

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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