YBOX1 Antibody

Datasheet
Code CSB-PA026247XA01MO
Product Type Polyclonal Antibody
Uniprot No. P62960
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Mus musculus (Mouse) YBOX1 protein
Raised in Rabbit
Species Reactivity Mus musculus (Mouse)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Nuclease-sensitive element-binding protein 1 (CCAAT-binding transcription factor I subunit A) (CBF-A) (DNA-binding protein B) (DBPB) (Enhancer factor I subunit A) (EFI-A) (Y-box transcription factor) (Y-box-binding protein 1) (YB-1) Ybx1 Msy-1 Msy1 Nsep1 Yb1
Immunogen Species Mus musculus (Mouse)
Gene Names Ybx1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Mediates pre-mRNA alternative splicing regulation. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. Regulates the transcription of numerous genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds preferentially to 5'-[CU]CUGCG-3' motif in vitro (By similarity).
Subcellular Location Cytoplasm, Nucleus, Cytoplasmic granule, Secreted
Tissue Specificity Expressed at high levels in the testis. Present in the mRNP particles that mediate the storage and masking of mRNAs during spermiogenesis.
Database Links

KEGG: mmu:22608

STRING: 10090.ENSMUSP00000078589

UniGene: Mm.258204

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