yjjJ Antibody

Code CSB-PA334558XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) yjjJ Polyclonal antibody
Uniprot No.
Target Names
yjjJ
Alternative Names
yjjJ antibody; b4385 antibody; JW4348Toxin YjjJ antibody; Putative DNA-binding transcriptional regulator YjjJ antibody; Putative serine/threonine kinase toxin YjjJ antibody; EC 2.-.-.- antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) yjjJ protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Toxic when overexpressed in E.coli, leading to long filamentous cells. The toxic effect is neutralized by non-cognate antitoxin HipB. Does not seem to inhibit DNA, RNA or protein synthesis, and unlike paralogous toxin HipA its toxic activity is not counteracted by overexpression of GltX. Binds DNA. Might be a protein kinase.
Gene References into Functions
  1. Despite being a homolog of HipA, YjjJ seems to have different cellular target(s) than that of HipA. HipB, the cognate antitoxin of HipA, also acts as an antitoxin for YjjJ. PMID: 28430938
Protein Families
HipA Ser/Thr kinase family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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