Human T-complex protein 1 subunit epsilon(CCT5) ELISA kit

Code CSB-EL004862HU
Size 96T,5×96T,10×96T
Price Request a Quote or Start an on-line Chat
Trial Size 24T ELISA Kit Trial Size (Only USD$150/ kit)
* The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now

Product Details

Target Name
chaperonin containing TCP1, subunit 5 (epsilon)
Alternative Names
CCT 5 ELISA Kit; CCT epsilon ELISA Kit; CCT-epsilon ELISA Kit; CCT5 ELISA Kit; CCTE ELISA Kit; CCTepsilon ELISA Kit; Chaperonin containing T-complex polypeptide 1; subunit 5 ELISA Kit; Chaperonin containing TCP 1 epsilon ELISA Kit; Chaperonin containing TCP 1 subunit 5 ELISA Kit; Chaperonin containing TCP 1 subunit 5 epsilon ELISA Kit; Chaperonin containing TCP1 epsilon ELISA Kit; Chaperonin containing TCP1 subunit 5 ELISA Kit; Chaperonin containing TCP1 subunit 5 epsilon ELISA Kit; KIAA0098 ELISA Kit; T complex protein 1 epsilon subunit ELISA Kit; T complex protein 1 subunit epsilon ELISA Kit; T-complex protein 1 subunit epsilon ELISA Kit; TCP 1 epsilon ELISA Kit; TCP-1-epsilon ELISA Kit; TCP1epsilon ELISA Kit; TCPE ELISA Kit; TCPE_HUMAN ELISA Kit
Abbreviation
CCT5
Uniprot No.
Species
Homo sapiens (Human)
Sample Types
serum, plasma,tissue homogenates, cell lysates
Detection Range
15.6 pg/mL-1000 pg/mL
Sensitivity
3.9 pg/mL
Assay Time
1-5h
Sample Volume
50-100ul
Detection Wavelength
450 nm
Research Area
Signal Transduction
Assay Principle
quantitative
Measurement
Sandwich
Precision

Linearity

Recovery

Typical Data

Troubleshooting
and FAQs
Storage
Store at 2-8°C. Please refer to protocol.
Lead Time
3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx
Description

This Human CCT5 ELISA Kit was designed for the quantitative measurement of Human CCT5 protein in serum, plasma,tissue homogenates, cell lysates. It is a Sandwich ELISA kit, its detection range is 15.6 pg/mL-1000 pg/mL and the sensitivity is 3.9 pg/mL.

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Target Background

Function
(From Uniprot)
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.
Gene References into Functions
  1. CCT5 complex caps mutant mHTT fibrils at their tips and encapsulates mHTT oligomers, providing a structural description of the inhibition of mHTTQ46-Ex1 by CCT5 complex and a shared mechanism of mHTT inhibition between TRiC chaperonin and the CCT5 complex PMID: 25995452
  2. H147R CCT5 was not as efficient in chaperoning these substrates as wild type CCT5. PMID: 25124038
  3. introduction of the truncated human CCT epsilon subunit into yeast cells PMID: 22232265
  4. A missense mutation within the CCT5 gene is associated with autosomal recessive mutilating sensory neuropathy with spastic paraplegia. PMID: 16399879
Involvement in disease
Neuropathy, hereditary sensory, with spastic paraplegia, autosomal recessive (HSNSP)
Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein Families
TCP-1 chaperonin family
Database Links

HGNC: 1618

OMIM: 256840

KEGG: hsa:22948

STRING: 9606.ENSP00000280326

UniGene: Hs.1600

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