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| Code | CSB-E09990h |
| Size | 96T,5×96T,10×96T |
| Price | Request a Quote or Start an on-line Chat |
| Trial Size |
24T ELISA Kit Trial Size (Only USD$150/ kit) * The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now |
This human GCP-2 ELISA kit employs the quantitative sandwich enzyme immunoassay technique to measure the levels of human GCP-2 in serum, plasma, or tissue homogenates. It also uses the enzyme-substrate chromogenic reaction to visualize and analyze the analyte levels through the color intensity. The intensity of the colored product is in direct proportion to the GCP-2 levels in the sample and is measured at 450 nm through a microplate reader.
GCP-2, also known as CXCL6, is a neutrophil-recruiting ELR+ chemokine that signals through the receptors CXCR1 and CXCR2 that are expressed on neutrophils. CXCL6-CXCR1/2 signaling mediates multiple biological processes such as inflammation, immunoreaction, cell growth, and metastasis in humans. It also promotes human hepatocyte proliferation through the CXCR1-NF-κB pathway and suppresses collagen I secretion by hepatic stellate cells. CXCL6 is involved in cancer angiogenesis, metastasis, and immune response. CXCL6 promotes the growth and metastasis of various cancers, including non-small cell lung cancer and osteosarcoma (OS).
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