Human midregional pro-atrial natriuretic peptide (MR-proANP) ELISA kit

Midregional pro-atrial natriuretic peptide (MR-proANP) is a stable fragment derived from the precursor of atrial natriuretic peptide, a hormone that cardiac atrial cells produce when blood volume and pressure increase. MR-proANP remains stable in circulation longer than the active ANP hormone. This makes it a valuable biomarker for cardiovascular assessment. Clinical researchers have focused on this peptide fragment because it can help diagnose heart failure, monitor cardiac function, and evaluate cardiovascular risk in different patient groups.

The Human midregional pro-atrial natriuretic peptide (MR-proANP) ELISA kit (CSB-EQ028056HU) uses a quantitative sandwich measurement principle to detect MR-proANP in human samples. This assay works with serum, plasma, and tissue homogenates. It has a detection range of 39 pmol/L to 2500 pmol/L and achieves a sensitivity of 9.8 pmol/L. The protocol needs 50-100 μL sample volume and takes 1-5 hours to complete, with detection at 450 nm wavelength.

Application Examples

Note: The following application examples are drawn from a selection of publications citing this product. For additional applications, please refer to the full list of references in the "Citations" section.

Cardiovascular researchers have used this ELISA kit to measure midregional pro-atrial natriuretic peptide levels in human blood samples. The assay has supported studies that examine cardiac biomarkers in clinical settings, adding to comprehensive biomarker profiling alongside other cardiovascular indicators.

• Cardiovascular biomarker research: Quantifies midregional pro-atrial natriuretic peptide in plasma samples as part of multi-biomarker panels for cardiac assessment
• Clinical diagnostic studies: Applied in hospital-based research involving blood sample analysis from patients undergoing routine clinical evaluations
• Cardiac function assessment: Used alongside other natriuretic peptides and cardiac markers to evaluate heart-related biomarker profiles in human subjects