Does your kit quantify the whole human haptoglobin or specific subgroup?
"Recently, Fasano’s group identified the molecular identity of zonulin as prehaptoglobin-2 (pre-HP2).47"
Reference 47 is
47. Tripathi A, Lammers KM, Goldblum S, Shea-Donohue T, Netzel-Arnett S, Buzza MS, Antalis TM, Vogel SN, Zhao A, Yang S, et al. Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2. Proc Natl Acad Sci U S A 2009; 106:16799-804http://dx.doi.org/10.1073/pnas.0906773106; PMID:19805376
Can you help us to quantify only prehaptoglobin-2 only? If we quantify all haptoglobin, the other haptoglobins will dilute actual zonulin level.
If this kit isn’t suitable for the needs, perhaps do you have another one, which can detect only prehaptoglobin-2? Please advise.