Mouse Alpha-2-macroglobulin(A2M) ELISA kit

Code CSB-EL001004MO
Size 96T,5×96T,10×96T
Trial Size 24T ELISA kits trial application
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Product Details

Description

This Mouse A2M ELISA Kit was designed for the quantitative measurement of Mouse A2M protein in serum, plasma. It is a Competitive ELISA kit, its detection range is 0.156 μg/mL-10 μg/mL and the sensitivity is 0.039 μg/mL.

Target Name alpha-2-macroglobulin
Alternative Names Pzp ELISA Kit; A2m ELISA Kit; Pregnancy zone protein ELISA Kit; Alpha-2-macroglobulin ELISA Kit; Alpha-2-M) [Cleaved into: Alpha-2-macroglobulin 165 kDa subunit; Alpha-2-macroglobulin 35 kDa subunit] ELISA Kit
Abbreviation A2M
Uniprot No. Q61838
Species Mus musculus (Mouse)
Sample Types serum, plasma
Detection Range 0.156 μg/mL-10 μg/mL
Sensitivity 0.039 μg/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Immunology
Assay Principle quantitative
Measurement Competitive
ELISA Data Analysis Watch ELISA data processing video & download Curve Expert if needed
Troubleshooting
and FAQs
ELISA kit FAQs
Storage Store at 2-8°C. Please refer to protocol.
Lead Time 3-5 working days

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Target Background

Function
(From Uniprot)
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region, a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
Subcellular Location Secreted.
Protein Families Protease inhibitor I39 (alpha-2-macroglobulin) family
Tissue Specificity Highest expression in liver, medium expression in ovary, heart and stomach. Low expression in lung, kidney and uterus. Protein found in plasma.
Database Links

STRING: 10090.ENSMUSP00000107760

UniGene: Mm.260144

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