Mouse Carbonic anhydrase 3(CA3) ELISA kit

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Code	CSB-EL004371MO
Size	96T,5×96T,10×96T
Trial Size
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Product Details

Target Name	carbonic anhydrase III, muscle specific
Alternative Names	Ca3 ELISA Kit; Car3Carbonic anhydrase 3 ELISA Kit; EC 4.2.1.1 ELISA Kit; Carbonate dehydratase III ELISA Kit; Carbonic anhydrase III ELISA Kit; CA-III ELISA Kit
Abbreviation	CA3
Uniprot No.	P16015
Species	Mus musculus (Mouse)
Sample Types	serum, plasma, tissue homogenates
Detection Range	4.69 pg/mL-300 pg/mL
Sensitivity	1.17 ng/mL
Assay Time	1-5h
Sample Volume	50-100ul
Detection Wavelength	450 nm
Research Area	Cell Biology
Assay Principle	quantitative
Measurement	Sandwich
Troubleshooting and FAQs	ELISA kit FAQs
Storage	Store at 2-8°C. Please refer to protocol.
Lead Time	7-14 working days

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Function	Reversible hydration of carbon dioxide.
Gene References into Functions	CAIII is highly expressed in osteocytes, is regulated by parathyroid hormone both in vitro and in vivo, and protects osteocytes from oxidative stress. PMID: 28928248 Our results indicate that Car3 is not required for de novo lipogenesis, and Car3 knockout mice fed high-fat diet do not have significant differences in responses to various diets to wild type mice. PMID: 28437447 The results suggest that elevated isoaspartate and CPS-1, and reduced CA-III levels could serve as biomarkers of hepatocellular injury. PMID: 25684186 We conclude that down-regulation of CAIII in preadipocytes enhances adipogenesis and that CAIII is a regulator of adipogenic differentiation which acts at the level of PPAR-gamma2 gene expression. PMID: 22507175 Mice lacking carbonic anhydrase III were viable and fertile and had normal life spans. PMID: 15509796 lack of proximal tubule cLCN5 in mice and men is associated with CAIII induction, increased cell proliferation, and oxidative stress PMID: 18322545 Show More Hide All
Subcellular Location	Cytoplasm
Protein Families	Alpha-carbonic anhydrase family
Tissue Specificity	Expressed at lower levels in adipose tissue from animals that were either genetically obese or had experimentally induced obesity.
Database Links	KEGG: mmu:12350 STRING: 10090.ENSMUSP00000029076 UniGene: Mm.300

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