Mouse Carbonic anhydrase 3(CA3) ELISA kit

Code CSB-EL004371MO
Size 96T,5×96T,10×96T
Trial Size 24T ELISA kits trial application
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Product Details

Target Name carbonic anhydrase III, muscle specific
Alternative Names Ca3 ELISA Kit; Car3Carbonic anhydrase 3 ELISA Kit; EC ELISA Kit; Carbonate dehydratase III ELISA Kit; Carbonic anhydrase III ELISA Kit; CA-III ELISA Kit
Abbreviation CA3
Uniprot No. P16015
Species Mus musculus (Mouse)
Sample Types serum, plasma, tissue homogenates
Detection Range 4.69 pg/mL-300 pg/mL
Sensitivity 1.17 ng/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Cell Biology
Assay Principle quantitative
Measurement Sandwich
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Storage Store at 2-8°C. Please refer to protocol.
Lead Time 7-14 working days

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Target Data

Function Reversible hydration of carbon dioxide.
Gene References into Functions
  1. CAIII is highly expressed in osteocytes, is regulated by parathyroid hormone both in vitro and in vivo, and protects osteocytes from oxidative stress. PMID: 28928248
  2. Our results indicate that Car3 is not required for de novo lipogenesis, and Car3 knockout mice fed high-fat diet do not have significant differences in responses to various diets to wild type mice. PMID: 28437447
  3. The results suggest that elevated isoaspartate and CPS-1, and reduced CA-III levels could serve as biomarkers of hepatocellular injury. PMID: 25684186
  4. We conclude that down-regulation of CAIII in preadipocytes enhances adipogenesis and that CAIII is a regulator of adipogenic differentiation which acts at the level of PPAR-gamma2 gene expression. PMID: 22507175
  5. Mice lacking carbonic anhydrase III were viable and fertile and had normal life spans. PMID: 15509796
  6. lack of proximal tubule cLCN5 in mice and men is associated with CAIII induction, increased cell proliferation, and oxidative stress PMID: 18322545

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Subcellular Location Cytoplasm
Protein Families Alpha-carbonic anhydrase family
Tissue Specificity Expressed at lower levels in adipose tissue from animals that were either genetically obese or had experimentally induced obesity.
Database Links

KEGG: mmu:12350

STRING: 10090.ENSMUSP00000029076

UniGene: Mm.300


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