This Mouse CA3 ELISA Kit was designed for the quantitative measurement of Mouse CA3 protein in serum, plasma, tissue homogenates. It is a Sandwich ELISA kit, its detection range is 4.69 pg/mL-300 pg/mL and the sensitivity is 1.17 ng/mL.
CAIII is highly expressed in osteocytes, is regulated by parathyroid hormone both in vitro and in vivo, and protects osteocytes from oxidative stress. PMID: 28928248
Our results indicate that Car3 is not required for de novo lipogenesis, and Car3 knockout mice fed high-fat diet do not have significant differences in responses to various diets to wild type mice. PMID: 28437447
The results suggest that elevated isoaspartate and CPS-1, and reduced CA-III levels could serve as biomarkers of hepatocellular injury. PMID: 25684186
We conclude that down-regulation of CAIII in preadipocytes enhances adipogenesis and that CAIII is a regulator of adipogenic differentiation which acts at the level of PPAR-gamma2 gene expression. PMID: 22507175
Mice lacking carbonic anhydrase III were viable and fertile and had normal life spans. PMID: 15509796
lack of proximal tubule cLCN5 in mice and men is associated with CAIII induction, increased cell proliferation, and oxidative stress PMID: 18322545
Alpha-carbonic anhydrase family
Expressed at lower levels in adipose tissue from animals that were either genetically obese or had experimentally induced obesity.