Mouse Carbonic anhydrase 3(CA3) ELISA kit

Code CSB-EL004371MO
Size 96T,5×96T,10×96T
Price Request a Quote or Start an on-line Chat
Trial Size 24T ELISA Kit Trial Size (Only USD$150/ kit)
* The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now

Product Details

Target Name
carbonic anhydrase III, muscle specific
Alternative Names
Ca3 ELISA Kit; Car3Carbonic anhydrase 3 ELISA Kit; EC 4.2.1.1 ELISA Kit; Carbonate dehydratase III ELISA Kit; Carbonic anhydrase III ELISA Kit; CA-III ELISA Kit
Abbreviation
CA3
Uniprot No.
Species
Mus musculus (Mouse)
Sample Types
serum, plasma, tissue homogenates
Detection Range
4.69 pg/mL-300 pg/mL
Sensitivity
1.17 ng/mL
Assay Time
1-5h
Sample Volume
50-100ul
Detection Wavelength
450 nm
Research Area
Cell Biology
Assay Principle
quantitative
Measurement
Sandwich
Troubleshooting
and FAQs
Storage
Store at 2-8°C. Please refer to protocol.
Lead Time
3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx
Description

This Mouse CA3 ELISA Kit was designed for the quantitative measurement of Mouse CA3 protein in serum, plasma, tissue homogenates. It is a Sandwich ELISA kit, its detection range is 4.69 pg/mL-300 pg/mL and the sensitivity is 1.17 ng/mL.

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Target Background

Function
(From Uniprot)
Reversible hydration of carbon dioxide.
Gene References into Functions
  1. CAIII is highly expressed in osteocytes, is regulated by parathyroid hormone both in vitro and in vivo, and protects osteocytes from oxidative stress. PMID: 28928248
  2. Our results indicate that Car3 is not required for de novo lipogenesis, and Car3 knockout mice fed high-fat diet do not have significant differences in responses to various diets to wild type mice. PMID: 28437447
  3. The results suggest that elevated isoaspartate and CPS-1, and reduced CA-III levels could serve as biomarkers of hepatocellular injury. PMID: 25684186
  4. We conclude that down-regulation of CAIII in preadipocytes enhances adipogenesis and that CAIII is a regulator of adipogenic differentiation which acts at the level of PPAR-gamma2 gene expression. PMID: 22507175
  5. Mice lacking carbonic anhydrase III were viable and fertile and had normal life spans. PMID: 15509796
  6. lack of proximal tubule cLCN5 in mice and men is associated with CAIII induction, increased cell proliferation, and oxidative stress PMID: 18322545

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Subcellular Location
Cytoplasm.
Protein Families
Alpha-carbonic anhydrase family
Tissue Specificity
Expressed at lower levels in adipose tissue from animals that were either genetically obese or had experimentally induced obesity.
Database Links

KEGG: mmu:12350

STRING: 10090.ENSMUSP00000029076

UniGene: Mm.300

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