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| Code | CSB-E08386m |
| Size | 96T,5×96T,10×96T |
| Price | Request a Quote or Start an on-line Chat |
| Trial Size |
24T ELISA Kit Trial Size (Only USD$150/ kit) * The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now |
CUSABIO's mouse cystatin C (Cys-C) ELISA kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse Cys-C in serum, plasma, or tissue homogenates. This assay uses the sandwich enzyme immunoassay technique in combination with the enzyme-substrate chromogenic reaction to quantify the analyte in the sample. The color develops positively to the amount of Cys-C in samples. The color intensity is measured at 450 nm via a microplate reader.
Cys-C (CST3) is a nonglycosylated protein produced at a constant degree in all nucleated cells and spontaneously crosses the glomerular membrane, being reabsorbed and broken down in the proximal tubular cells of the kidney, without extrarenal elimination. Compared to serum creatinine, Cys-C is thought to be a more accurate measure of kidney function because its levels do not depend on muscle mass, age, and gender, and are not influenced by inflammatory disorders or malignancy. Assessment of Cys-C levels could be valued in the early prediction of renal dysfunction as they increase faster than creatinine levels as the GFR declines. Additionally, Cys-C shows the potential to be an earlier marker for acute kidney injury, a superior marker of kidney transplant function, as well as cardiovascular disease (CVD) risk and transplant failure.
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