Mouse chemokine (C-C motif) ligand 1 ELISA Kit

Code CSB-E14298m
Size 96T,5×96T,10×96T
Trial Size 24T ELISA kits trial application
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Product Details

Target Name chemokine (C-C motif) ligand 1
Alternative Names Ccl1 ELISA kit; Scya1 ELISA kit; Tca3C-C motif chemokine 1 ELISA kit; P500 ELISA kit; SIS-epsilon ELISA kit; Small-inducible cytokine A1 ELISA kit; T-cell activation protein 3 ELISA kit; TCA-3 ELISA kit; TCA3 ELISA kit
Abbreviation CCL1
Uniprot No. P10146
Species Mus musculus (Mouse)
Detection Range Request Information
Sensitivity Request Information
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Immunology
and FAQs
Storage Store at 2-8°C. Please refer to protocol.
Lead Time 3-5 working days

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Target Data

Function Cytokine that is chemotactic for neutrophils.
Gene References into Functions
  1. Findings provide evidence that CCL1 possibly contributes to 5-fluorouracil/paclitaxel chemoresistance in CT26 colorectal cell line via TGF-beta and nuclear factor-kappa B signaling pathways. PMID: 28934847
  2. Sca-1(+) progenitor cells found to exhibit increased migration was associated with elevated levels of chemokines, CCL2 (chemokine (C-C motif) ligand 2) and CXCL1 (chemokine (C-X-C motif) ligand 1), and their corresponding receptors. PMID: 27300479
  3. Study reports showing that I. ricinus saliva can increase the production of three chemokines, CCL1, CCL2 and CXCL2. This upregulation reflects Th2 polarization of the host immunity due to the effect of tick saliva and in the case of CCL2 probably facilitates tick engorgement in the late, rapid feeding phase. PMID: 25545116
  4. Our data indicate that estradiol is important in regulating the effects of keratinocyte growth factor on mouse uterine epithelial cell secretion of CCL20 and CXCL1. PMID: 24807244
  5. CCL-1 is one of the key molecules in pathogenesis in neuropathic pain. PMID: 23788036
  6. These data identify a novel function for CCL1-CCR8 in metastasis and lymph node LECs as a critical checkpoint for the entry of metastases into the lymph nodes. PMID: 23878309
  7. Egr2-deficient mast cells were incapable of directing CD4(+) T cell migration via the CCL1-CCR8 axis. PMID: 23536637
  8. results indicate that CCL1 released from M2bM is essentially required for the maintenance of their properties PMID: 22730547
  9. C-terminal clipping of chemokine CCL1/I-309 enhances CCR8-mediated intracellular calcium release and anti-apoptotic activity PMID: 22479563
  10. These findings reveal the importance of CXCL1 produced by hematopoietic and resident cells in regulating pulmonary host defense against a bacterial pathogen PMID: 20937845
  11. neutralization of CCL1 can be used as an adjuvant to antitumor immunotherapy, as a means of reversing the immunosuppressive function of Tregs without compromising T cell effector function. PMID: 20483762
  12. increased responsivenss of murine eosiophils to TCA-3 is mediated by CCR8 receptor in mice PMID: 12050188
  13. After stimulation via high-affinity FcepsilonRI, the transcriptional levels of I-309 (CCL1), MIP-1alpha (CCL3) and MIP-1beta (CCL4) were found among the 10 most increased human and mouse transcripts from approximately 12 000 genes PMID: 12393595
  14. CCL1 is involved in the recruitment of eosinophils in several models of allergic inflammation, but it is not important for the recruitment of Th2 cells to the lung. PMID: 12707363
  15. Benzo(a)pyrene and an aryl hydrocarbon receptor agonist enhance activitity of te Ccl1 promoter. PMID: 16679317
  16. These data demonstrate that the chemokine TCA3/CCL1 is important to the pathogenesis of ischemic injury of experimental partial liver grafts. PMID: 17164723
  17. Mast cell-derived CCL1- and CCR8-expressing CD4-positive effector T lymphocytes play an essential role in orchestrating lung mucosal inflammatory responses. PMID: 17641040
  18. CCR8/CCL1 interaction may play a role in type 1 diabetes through macrophage recruitment and activation PMID: 17947648
  19. lovastatin-induced increase in regulatory T cells in inflamed skin was dependent on expression of CCL1, that is locally up-regulated by statin administration. PMID: 18714025
  20. In a novel mechanism, IL-12 augments naive CD8 T cell activation by facilitating CCL1 production by dendritic cells, thus promoting more stable cognate interactions during priming. PMID: 19050277

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Protein Families Intercrine beta (chemokine CC) family
Database Links

KEGG: mmu:20290

STRING: 10090.ENSMUSP00000103824

UniGene: Mm.1283


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