Mouse cross linked C-telopeptide of type I collagen (CTX-Ⅰ) ELISA Kit

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Mouse cross linked C-telopeptide of type I collagen (CTX-Ⅰ) ELISA Kit

Name: Mouse cross linked C-telopeptide of type I collagen (CTX-Ⅰ) ELISA Kit
Brand: CUSABIO
SKU: CSB-E12782m

Citations (37) Protocol

Code	CSB-E12782m
Size	96T,5×96T,10×96T
Price	Request a Quote
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Product Details
Citations (37)
Customer Reviews and Q&A

Alternative Names

cross linked C-telopeptide of type 1 collagen (CTX-1),_x000D_cross linked C-telopeptide of type I collagen (CTX-I)

Abbreviation

CTX-Ⅰ

Species

Mus musculus (Mouse)

Sample Types

serum, plasma, tissue homogenates.

Detection Range

0.23 ng/ml-15 ng/ml.

Sensitivity

0.12 ng/ml.

Assay Time

1-5h

Sample Volume

50-100ul

Detection Wavelength

450 nm

Research Area

Others

Assay Principle

quantitative

Measurement

Competitive

Precision

Linearity

To assess the linearity of the assay, samples were spiked with high concentrations of mouse CTX-Ⅰ in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.

	Sample	Serum(n=4)
1:1	Average %	84
	Range %	80-92
1:2	Average %	87
	Range %	81-94
1:4	Average %	88
	Range %	82-95
1:8	Average %	93
	Range %	86-98

Recovery

Typical Data

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

ng/ml

OD1

OD2

Average

0.195

0.204

0.200

7.5

0.246

0.260

0.253

3.75

0.339

0.348

0.344

1.87

0.518

0.529

0.524

0.94

0.851

0.841

0.846

0.47

1.272

1.253

1.262

0.23

1.838

1.784

1.811

2.512

2.525

2.518

ELISA Data Analysis

ELISA Standard Curve & Curve Expert software

Troubleshooting
and FAQs

ELISA kit FAQs

Storage

Store at 2-8°C. Please refer to protocol.

Shelf Life

6 months

Lead Time

3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx.

Description

This Mouse CTX-Ⅰ ELISA Kit was designed for the quantitative measurement of Mouse CTX-Ⅰ protein in serum, plasma, tissue homogenates. It is a Competitive ELISA kit, its detection range is 0.23 ng/ml-15 ng/ml and the sensitivity is 0.12 ng/ml.

Aqueous extract of Sedum sarmentosum (SS-Ex) promotes bone formation and linear bone growth in a calcium/vitamin D-deficient mouse model DH Jung, HJ Kim, JA Ryuk, BS Ko, YB Kim,Biomedicine & Pharmacotherapy,2025
“Betaone” barley water extract suppresses ovariectomy-induced osteoporosis in vivo and RANKL-induced osteoclast differentiation in vitro Y Lee, HJ Lee, KJ Kim, HB Shin, YA Shin, H Jin,PloS one,2025
Stephanine Protects Against Osteoporosis by Suppressing Osteoclastogenesis via Inhibition of the RANKL—RANK Interaction T Liu, J Li, M Duan, Y Wang, Z Jiang,Journal of Cellular and Molecular Medicine,2024
Altered post-fracture systemic bone loss in a mouse model of osteocyte dysfunction B Osipov, AJ Emami, HC Cunningham, S Orr,JBMR plus,2024
FOXO1-mTOR pathway in vascular pericyte regulates the formation of type H vessels to control bone metabolism C Cheng, M Deng, C Cheng, H Wu, Y Wang,Journal of Orthopaedic Translation,2024
Loss of ZC4H2, an Arthrogryposis Multiplex Congenita Associated Gene, Promotes Osteoclastogenesis in Mice L Zhu, L Zhang, J Cha, C Li, B Mao,Genes,2024
PCLAF induces bone marrow adipocyte senescence and contributes to skeletal aging L Xie,Bone research,2024
Oleanolic acid exerts bone anabolic effects via activation of osteoblastic 25-hydroxyvitamin D 1-alpha hydroxylase WX Yu,Biomedicine & pharmacotherapy,2024
Activation of TAZ by XMU-MP-1 inhibits osteoclastogenesis and attenuates ovariectomy-induced cancellous bone loss X Li,Biochemical and biophysical research communications,2023
Icariin, a phytoestrogen, exerts rapid estrogenic actions through crosstalk of estrogen receptors in osteoblasts KY Wong,Phytotherapy research,2023
Cervical vertebrae for early bone loss evaluation in osteoporosis mouse models B Teng,Quantitative imaging in medicine and surgery,2023
Simvastatin therapy in higher dosages deteriorates bone quality: Consistent evidence from population-wide patient data and interventional mouse studies M Leutner,Biomedicine & pharmacotherapy,2022
Asiatic acid improves high-fat-diet-induced osteoporosis in mice via regulating SIRT1/FOXO1 signaling and inhibiting oxidative stress X Chen,Histology and histopathology,2022
The effects of metformin and alendronate in attenuating bone loss and improving glucose metabolism in diabetes mellitus mice Q Zhou,Aging (Albany NY),2022
Age-related accumulation of advanced oxidation protein products promotes osteoclastogenesis through disruption of redox homeostasis J Zhuang,cell death & disease,2021
SIS3 suppresses osteoclastogenesis and ameliorates bone loss in ovariectomized mice by modulating Nox4-dependent reactive oxygen species Wenzheng Pan,Biochemical pharmacology,2021
Conditional Knockout of PDK1 in Osteoclasts Suppressed Osteoclastogenesis and Ameliorated Prostate Cancer-Induced Osteolysis Y Zhang,Researchsquare,2021
DUSP6 expression is associated with osteoporosis through the regulation of osteoclast differentiation via ERK2/Smad2 signaling B Zhang,Cell death & disease,2021
Conditional knockout of the PDK‐1 gene in osteoblasts affects osteoblast differentiation and bone formation Y Bai,Journal of Cellular Physiology,2021
Deficiency of PDK1 in osteoclasts delays fracture healing and repair D Xiao,Molecular Medicine Reports,2020
Hydrogen sulfide protects against particle‐induced inflammatory response and osteolysis via SIRT1 pathway in prosthesis loosening Liu L,FASEB,2020
Catalpol suppresses osteoclastogenesis and attenuates osteoclast-derived bone resorption by modulating PTEN activity Meng J, et al,Biochemical Pharmacology,2019
The emerging role of IMD 0354 on bone homeostasis by suppressing osteoclastogenesis and bone resorption, but without affecting bone formation Chen W, et al,Cell Death and Disease,2019
The Nrf2 activator RTA-408 attenuates osteoclastogenesis by inhibiting STING dependent NF-κb signaling Xuewu Sun, et al,Redox Biology,2019
A novel transgenic murine model with persistently brittle bones simulating osteogenesis imperfecta type I Yi Liu, et al,Bone,2019
Malt1 deficient mice develop osteoporosis independent of osteoclast-intrinsic effects of Malt1 deficiency Monajemi M, et al,Journal of Leukocyte Biology,2019
Absence of Dipeptidyl Peptidase 3 increases oxidative stress and causes bone loss Menale C, et al,Journal of Bone and Mineral Research,2019
Macrophage migration inhibitory factor (MIF) inhibitor 4-IPP suppresses osteoclast formation and promotes osteoblast differentiation through the inhibition of the NF-κB signaling pathway Zheng L, et al,faseb journal,2019
A novel anti-osteoporotic agent that protects against postmenopausal bone loss by regulating bone formation and bone resorption Yu-te Yang .et al,Life Sciences,2018
Apolipoprotein E plays crucial roles in maintaining bone mass by promoting osteoblast differentiation via ERK1/2 pathway and by suppressing osteoclast differentiation via c-Fos, NFATc1, and NF-κB pathway TakaakiNoguchi.et al,Biochemical and Biophysical Research Communications,2018
VEGF-C promotes the development of lymphatics in bone and bone loss Devon Hominick.et al,Elife. 2018,2018
A Novel Diterpenoid Suppresses Osteoclastogenesis and Promotes Osteogenesis by Inhibiting Ifrd1-and IkBa-Mediated p65 Nuclear Translocation /,Journal of Bone and Mineral Research ,2017
Progranulin plays crucial roles in preserving bone mass by inhibiting TNF-a-induced osteoclastogenesis and promoting osteoblastic differentiation in mice Noguchi T. et al,Biochem Biophys Res Commun,2015
Progranulin plays crucial roles in preserving bone mass by inhibiting TNF-a-induced osteoclastogenesis and promoting osteoblastic differentiation in mice Noguchi T. et al,Biochem Biophys Res Commun,2015
Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice Khorasani MS.et al,Arthritis Res Ther.,2015
HYPOXIA-REPERFUSION AFFECTS OSTEOGENIC LINEAGE AND PROMOTES SICKLE CELL BONE DISEASE Dalle Carbonare L. et al,Blood,2015
Altered bone development in a mouse model of peripheral sensory nerve inactivation. Heffner MA et al,J Musculoskelet Neuronal Interact,2014

Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.

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What's the antibody information of this kit?

Thanks for your inquiry. Pls check our information: CSB-E12782m: Coated anti. Goat against rabbit secondary antibody; Specific anti: Rabbit polyclonal antibody
Coated anti. Goat against rabbit secondary antibody; Antigen Specific anti: Rabbit polyclonal antibody. Pls let me know if you have any further questions. Thank you.

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