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Mouse sex hormone-binding globulin,SHBG ELISA Kit

Protocol
Code CSB-E08233m
Size 96T,5×96T,10×96T
Price Request a Quote
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Product Details

Alternative Names
Shbg ELISA Kit; Sex hormone-binding globulin ELISA Kit; SHBG ELISA Kit; Sex steroid-binding protein ELISA Kit; SBP ELISA Kit; Testis-specific androgen-binding protein ELISA Kit; ABP ELISA Kit
Abbreviation
SHBG
Uniprot No.
P97497
Species
Mus musculus (Mouse)
Sample Types
serum, plasma
Detection Range
1 ng/mL-50 ng/mL
Sensitivity
0.5 ng/mL
Assay Time
1-5h
Sample Loading Volume
50-100ul
Detection Wavelength
450 nm
Research Area
Signal Transduction
Assay Principle
quantitative
Measurement
Sandwich
Precision

Linearity

Recovery

Typical Data

ELISA Data Analysis
ELISA Standard Curve & Curve Expert software
Troubleshooting
and FAQs
ELISA kit FAQs
Storage
Store at 2-8°C. Please refer to protocol.
Shelf Life
6 months
Lead Time
3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx.
Description

This Mouse SHBG ELISA Kit was designed for the quantitative measurement of Mouse SHBG protein in serum, plasma. It is a Sandwich ELISA kit, its detection range is 1.3 ng/mL-50 ng/mL and the sensitivity is 0.33 ng/mL.

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Shbg Proteins

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Target Background

Function
(From Uniprot)
Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
Gene References into Functions
  1. SHBG suppresses inflammation and lipid accumulation in macrophages and adipocytes, which might be among the mechanisms underlying the protective effect of SHBG, that is, its actions which reduce the incidence of metabolic syndrome PMID: 30046278
  2. A wave of apoptosis during the pre-pubertal period is required for normal spermatogenesis to develop, and our data indicate that this apoptotic wave may be regulated by ABP and/or androgens. PMID: 12831397
  3. USF transcription factors repress SHBG transcription in Sertoli cells through an interaction with FP4 within its proximal promoter PMID: 15574421
  4. monosaccharide-induced lipogenesis reduced hepatic HNF-4alpha levels, which in turn attenuated SHBG expression. PMID: 17992261
Subcellular Location
Secreted.
Database Links
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