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Mouse thymus activation regulated chemokine,TARC ELISA Kit

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Citations (6) Protocol MSDS
Code CSB-E14144m
Size 96T,5×96T,10×96T
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Product Details

Target Name
thymus activation regulated chemokine,TARC
Abbreviation
TARC/CCL17
Species
Mus musculus (Mouse)
Sample Types
serum, plasma, cell culture supernates, tissue homogenates
Detection Range
31.25 pg/mL-2000 pg/mL
Sensitivity
10.512 pg/mL
Assay Time
1-5h
Sample Volume
50-100ul
Detection Wavelength
450 nm
Research Area
Immunology
Assay Principle
quantitative
Measurement
Sandwich
ELISA Data Analysis
ELISA Standard Curve & Curve Expert software
Troubleshooting
and FAQs
ELISA kit FAQs
Storage
Store at 2-8°C. Please refer to protocol.
Shelf Life
6 months
Lead Time
3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx.
Description

The product CSB-E14144m is a sandwich ELISA kit developed to measure levels of mouse thymus activation regulated chemokine (TARC) in multiple samples, including serum, plasma, cell culture supernates, or tissue homogenates. The enzyme-substrate chromogenic reaction is also used to amplify the signal and quantify the levels of the analyte through the intensity of the colored product. The color intensity positively correlates with the amount of TARC bound in the initial step.

TRAC, also called CCL17, is a chemokine responsible for trafficking Th2 cells into sites of allergic inflammation. It promotes chemotaxis of effector T cells and supports DC-T cell interactions as well as DC migration towards TRAC-ligands. TARC binds specifically to CCR4 with high affinity and is involved in the trafficking of Th2 cells in eosinophil-associated disorders, including AA and AD, and presumably of neoplastic cells in certain T cell lymphomas such as angioimmunoblastic T cell lymphoma (AITL), mycosis fungoides (MF), and Sezary syndrome (SS). Lorenz Fülle et al. proved that TARC exerts a neuroimmune modulatory function and is expressed in hippocampal neurons through mouse models.

Citations

Related Products

CCL17 ELISA kits

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