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Pig Hepcidin(HAMP) ELISA kit

Citations (1) Protocol
Code CSB-EL010124PI
Size 96T,5×96T,10×96T
Price Request a Quote or Start an on-line Chat
Trial Size 24T ELISA Kit Trial Size (Only USD$150/ kit)
* The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now

Product Details

Target Name
hepcidin antimicrobial peptide
Alternative Names
HAMP ELISA Kit; Hepcidin ELISA Kit
Abbreviation
HAMP
Uniprot No.
Q8MJ80
Species
Sus scrofa (Pig)
Sample Types
serum, plasma, tissue homogenates
Detection Range
9.38 ng/mL-600 ng/mL
Sensitivity
2.34 ng/mL
Assay Time
1-5h
Sample Volume
50-100ul
Detection Wavelength
450 nm
Research Area
Cardiovascular
Assay Principle
quantitative
Measurement
Sandwich
ELISA Data Analysis
ELISA Standard Curve & Curve Expert software
Troubleshooting
and FAQs
ELISA kit FAQs
Storage
Store at 2-8°C. Please refer to protocol.
Lead Time
3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx
Description

This Pig HAMP ELISA Kit was designed for the quantitative measurement of Pig HAMP protein in serum, plasma, tissue homogenates. It is a Sandwich ELISA kit, its detection range is 9.38 ng/mL-600 ng/mL and the sensitivity is 2.34 ng/mL.

Citations

Related Products

HAMP Proteins

Customer Reviews and Q&A

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Target Background

Function
(From Uniprot)
Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin/SLC40A1, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes.; Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa.
Gene References into Functions
  1. this study demonstrates that urine hepcidin-25 concentrations strongly correlate with hepatic hepcidin mRNA abundance, plasma hepcidin-25 levels, iron transferrin saturation and non-heme liver iron levels. PMID: 26323096
  2. Data suugest that hepcidin might had antiinflammatory function and is a candidate regulator of the cross-talk between iron regulation and inflammation. PMID: 25774043
  3. report the full-length cDNA sequences of porcine hepcidin and liver-expressed antimicrobial peptide-2 (LEAP-2) PMID: 16051358
Subcellular Location
Secreted.
Protein Families
Hepcidin family
Database Links
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