Rat Follistatin-related protein 1(FSTL1) ELISA kit

Code CSB-EL009025RA
Size 96T,5×96T,10×96T
Price Request a Quote or Start an on-line Chat
Trial Size 24T ELISA Kit Trial Size (Only USD$150/ kit)
* The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now

Product Details

Target Name
follistatin-like 1
Alternative Names
Fstl1 ELISA kit; FrpFollistatin-related protein 1 ELISA kit; Follistatin-like protein 1 ELISA kit
Abbreviation
FSTL1
Uniprot No.
Species
Rattus norvegicus (Rat)
Sample Types
serum, plasma,tissue homogenates
Detection Range
15.6 ng/mL-1000 ng/mL
Sensitivity
3.9 ng/mL
Assay Time
1-5h
Sample Volume
50-100ul
Detection Wavelength
450 nm
Research Area
Cardiovascular
Assay Principle
quantitative
Measurement
Sandwich
Troubleshooting
and FAQs
Storage
Store at 2-8°C. Please refer to protocol.
Lead Time
3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx
Description

This Rat FSTL1 ELISA Kit was designed for the quantitative measurement of Rat FSTL1 protein in serum, plasma,tissue homogenates. It is a Sandwich ELISA kit, its detection range is 15.6 ng/mL-1000 ng/mL and the sensitivity is 3.9 ng/mL.

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Target Background

Function
(From Uniprot)
Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation. Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter. Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes. Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors.
Gene References into Functions
  1. exercise increased the cross-sectional area of myocytes and FSTL1 expression. Importantly, exercise increased circulating FSTL1 levels, which were positively correlated with the skeletal muscle FSTL1 expression and negatively correlated with heart fibrosis PMID: 27561749
  2. Decreased expression of Fstl1 in alveolar epithelium may disrupt alveolarization and pulmonary surfactant production, thus contributing to the development of pulmonary hypertension in the nitrofen-induced rat congenital diaphragmatic hernia model. PMID: 28188034
  3. our findings indicate that FSTL1 may contribute to neuronal survival after brain ischemia PMID: 25139876
  4. Characterization of follistatin-related gene: effects of estrous cycle stage and pregnancy on its messenger RNA expression in reproductive tissues. PMID: 12493714
  5. Expression levels of FLRG protein are significantly increased in brain damaged regions after penetrating injury; specifically, FLRG protein is colocalized in glial fibrillary acidic protein-positive reactive astroglial cells. PMID: 12645077
  6. Follistatin-like 1 (FSTL1) transcript is overexpressed in tolerated allografts compared to rejected allografts or syngeneic grafts PMID: 18925901

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Subcellular Location
Secreted.
Database Links
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