Recombinant Mouse Interleukin-7 protein(Il7) (Active)

In Stock
Code CSB-AP003331MO
Product Type Interleukin
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P10168
Lead Time 5-10 business days
Image
Storage Buffer 0.2 μm filtered PBS, pH 7.4, 2 % trehalose ,lyophilized
Alias IL-7
Species Mus musculus (Mouse)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine 2E8 cells is less than 0.2 ng/ml, corresponding to a specific activity of >5.0x106 IU/mg.
Purity >96% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence ECHIKDKEGK AYESVLMISI DELDKMTGTD SNCPNNEPNF FRKHVCDDTK EAAFLNRAAR KLKQFLKMNI SEEFNVHLLT VSQGTQTLVN CTSKEEKNVK EQKKNDACFL KRLLREIKTC WNKILKGSI
Research Area Immunology
Source E.coli
Gene Names Il7
Expression Region 26-154aa
Tag Info Tag-Free
Mol. Weight 14.9 kDa
Protein Description Full Length of Mature Protein
PubMed ID 3259677; 2329282
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Function Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation.
Subcellular Location Secreted
Protein Families IL-7/IL-9 family
Database Links

KEGG: mmu:16196

STRING: 10090.ENSMUSP00000126219

UniGene: Mm.3825

Pathway Jak-STAT signaling pathway
PI3K-Akt signaling pathway
Hematopoietic cell lineage

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