Code | CSB-MA634481 |
Size | US$166 |
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Application | Recommended Dilution |
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IHC | 1:20-1:200 |
The KRT7 monoclonal antibody was produced using hybridoma technology, which involves fusing B cells from the spleen of a mouse immunized with a synthesized peptide derived from human KRT7 with myeloma cells. The resulting hybridoma cells were screened for the clones that produce KRT7 antibodies. These selected hybridoma cells were then cultured in the mouse abdominal cavity to produce KRT7 monoclonal antibodies. The KRT7 monoclonal antibody was purified from mouse ascites using affinity chromatography with a specific immunogen to ensure its purity. The purified antibody has been validated for use in ELISA and IHC applications.
KRT7 is mainly expressed in epithelial cells, such as the cells lining the bladder, gastrointestinal tract, and bile ducts. Its main function is to provide structural support to these cells and to help maintain their mechanical integrity. KRT7 has been shown to play a role in cell signaling, cell differentiation, and cell migration, and it has also been implicated in the development of certain types of cancer.
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