Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
| Code | CSB-MA882135A0m |
| Size | US$210 |
| Order now | |
| Image |
|
| Have Questions? | Leave a Message or Start an on-line Chat |
| Application | Recommended Dilution |
|---|---|
| WB | 1:1000-1:5000 |
| IHC | 1:50-1:200 |
The MCM9 monoclonal antibody generation strats with the immunization of mice with recombinant human MCM9 protein (1-391aa). The selected hybridoma cells resulting from fusion of immunzied mice B cells with myeloma cells produce the specific MCM9 antibody. After isolation from mouse ascites, the MCM9 monoclonal antibody is purified to a high degree of purity using protein G affinity chromatography (95%+). This unconjugated IgG1 antibody is highly suitable for detecting the presence of human MCM9 protein in three applications, including ELISA, WB, and IHC.
MCM9 functions as a component of the MCM complex and is involved in homologous recombination repair of double-strand DNA breaks. It is essential for the proper formation of meiotic recombination intermediates, which are required for proper chromosome segregation during meiosis. MCM9 also plays a role in maintaining genomic stability by preventing the accumulation of DNA damage. Mutations in the MCM9 gene have been linked to a rare genetic disorder called primary ovarian insufficiency (POI).
There are currently no reviews for this product.
