MYCBP Monoclonal Antibody

Datasheet
Code CSB-MA8587101A0m
Product Type Monoclonal Antibody
Size US$350Purchase it in Cusabio online store
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Uniprot No. Q99417
Image
  • Immunohistochemical of paraffin-embedded Human testis tissue using CSB-MA8587101A0m at dilution of 1:200.

Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant Human MYCBP Protein
Raised in mouse
Species Reactivity Human
Specificity specific for human MYCBP denatured and native forms.
Tested Applications ELISA,IHC;Recommended dilution:IHC:1:50-1:500
Relevance The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene.
Form liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%,protein G purifed
Clonality monoclonal
Alias MYC Binding Protein,C-Myc Binding Protein,mycbp
Immunogen Species Homo sapiens (Human)
Gene Names MYCBP
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Clone No. 1D5D5
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Function May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC.
Subcellular Location Cytoplasm, Nucleus, Mitochondrion
Protein Families AMY1 family
Tissue Specificity Highly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low levels in lung.
Database Links

HGNC: 7554

OMIM: 606535

KEGG: hsa:26292

STRING: 9606.ENSP00000380702

UniGene: Hs.591506

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