MYCBP Monoclonal Antibody

Code CSB-MA8587101A0m
Size US$350Purchase it in Cusabio online store
(only available for customers from the US)
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  • Immunohistochemical of paraffin-embedded Human testis tissue using CSB-MA8587101A0m at dilution of 1:200.

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Product Details

Full Product Name mouse anti-Homo sapiens (Human) MYCBP monoclonal antibody
Uniprot No. Q99417
Target Names MYCBP
Alternative Names AMY 1 antibody; AMY-1 antibody; AMY1 antibody; Associate of Myc 1 antibody; C myc binding protein antibody; C-Myc-binding protein antibody; Cmyc binding protein antibody; MYCBP antibody; MYCBP_HUMAN antibody
Raised in mouse
Species Reactivity Human
Immunogen Recombinant Human MYCBP Protein
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality monoclonal
Clone No. 1D5D5
Purification Method >95%,protein G purifed
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form liquid
Tested Applications ELISA,IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:50-1:500
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
(From Uniprot)
May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC.
Gene References into Functions
  1. c-Myc expression is reduced in pterygium compared with normal conjunctiva. PMID: 22050566
  2. Suppression of telomerase activity mediated by PinX1 is involved in the Mad1/c-Myc pathway. PMID: 20544396
  3. miR-22 acts as a tumor suppressor through direct repression of MYCBP expression and subsequent reduction of oncogenic c-Myc activities. PMID: 20562918
  4. identified a novel AMY-1-binding protein, AAT-1, and determied its expression profiles, genes, and cellular localization; results showed that AAT-1 was specifically expressed in the testis throughout spermatogenesis and was also present in mature sperm PMID: 12223483
  5. interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits enzyme acdtivity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex PMID: 12414807
  6. AMY-1 coordinates ADP-Ribosylation Factors-mediated membrane trafficking and signaling pathways. PMID: 16866877
  7. An important role for MBP-1 in the altered cell proliferation and energy utilization that occur in response to an altered glucose concentration. PMID: 17595061
  8. AMY-1 was localized in the mitochondria of HeLa and sperm in association with AKAP149 and S-AKAP84, respectively. These results suggest that AMY-1 plays a role in spermatogenesis PMID: 11483602

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Subcellular Location Cytoplasm, Nucleus, Mitochondrion
Protein Families AMY1 family
Tissue Specificity Highly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low levels in lung.
Database Links

HGNC: 7554

OMIM: 606535

KEGG: hsa:26292

STRING: 9606.ENSP00000380702

UniGene: Hs.591506

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