Mouse anti-Human TNF alpha monoclonal antibody

Datasheet
Code CSB-MA074261A0m
Product Type Monoclonal Antibody
Size US$350
Immunogen Recombinant Human TNF alpha protein
Raised in mouse
Species Reactivity Human
Tested Applications WB,ELISA,IHC
Relevance Tumor necrosis factor alpha (TNF-¦Á), also known as cachectin and TNFSF1A, is the prototypic cytokine of the the TNF superfamily. It is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF-¦Á is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). Two receptors mediating the TNF-¦Á function have been identified, the ubiquitous TNF RI from which most signaling are derived, and the hematopoietic cell-restricted TNF RII. TNF-¦Á has been implicated in the pathogenesis of a variety of human diseases including autoimmune diseases, insulin resistance, and cancer.
Form liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method Caprylic Acid Ammonium Sulfate Precipitation purified
Isotype IgG2a
Clonality monoclonal
Alias TNF-a£¬Cachectin£¬Tumor necrosis factor ligand superfamily member 2
Protocols Western Blotting(WB) Protocol
ELISA Protocol
Immunohistochemistry (IHC) Protocol
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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