Mouse anti-Human TNF alpha monoclonal antibody

Code CSB-MA074261A0m
Product Type Monoclonal Antibody
Size US$350
Protocols Western Blotting(WB) Protocol
ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant Human TNF alpha protein
Raised in mouse
Species Reactivity Human
Tested Applications WB,ELISA,IHC
Relevance Tumor necrosis factor alpha (TNF-¦Á), also known as cachectin and TNFSF1A, is the prototypic cytokine of the the TNF superfamily. It is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF-¦Á is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). Two receptors mediating the TNF-¦Á function have been identified, the ubiquitous TNF RI from which most signaling are derived, and the hematopoietic cell-restricted TNF RII. TNF-¦Á has been implicated in the pathogenesis of a variety of human diseases including autoimmune diseases, insulin resistance, and cancer.
Form liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method Caprylic Acid Ammonium Sulfate Precipitation purified
Isotype IgG2a
Clonality monoclonal
Alias TNF-a£¬Cachectin£¬Tumor necrosis factor ligand superfamily member 2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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