RBP4 Monoclonal Antibody

Datasheet
Code CSB-MA070501A0m
Product Type Monoclonal Antibody
Size US$350Purchase it in Cusabio online store
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Image
  • All lanes: Mouse anti- human Retinol-binding protein 4 monoclonal antibody at 0.3μg/ml
    Lane 1: Human positive serum1:10
    Lane 2: Human positive serum1:100
    Secondary:HRP labeled Goat polyclonal to Mouse IgG at 1/3000 dilution
    Predicted band size : 23kd
    Observed band size : 27kd

  • All lanes: Mouse anti- human Retinol-binding protein 4 monoclonal antibody at 0.3μg/ml
    Lane 1:RBP4 transfected E.coli lysate
    Lane 2:Human positive serum1:100
    Lane 3:mouse liver tissue
    Secondary:HRP labeled Goat polyclonal to Mouse IgG at 1/3000 dilution
    Predicted band size : 23kd
    Observed band size : 27kd

  • Immunohistochemical of paraffin-embedded human hepatic tissue using CSB-MA070501A0m at dilution of 1:200

  • Immunohistochemical of paraffin-embedded human nephridial tissue using CSB-MA070501A0m at dilution of 1:200

Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant Human Retinol-binding protein 4 protein
Raised in mouse
Species Reactivity Human,Mouse
Specificity specific for native and denatured forms
Tested Applications ELISA,WB,IHC;Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500
Relevance Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.
Form liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%,Protein G purified
Isotype IgG1
Clonality monoclonal
Alias Plasma retinol-binding protein, PRBP, RBP, RBP4, PRO2222
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Clone No. 6A1C2
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