Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP). Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ELISA, WB, SDS-PAGE. Latex enhanced turbidimetric immunoassay (LETIA), immunogen and other possible
PBS, pH 7.4
Full length protein
Purified from Human urine
Human Beta-2-microglobulin protein
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.