Human Lactoferrin

Code CSB-NP008701h
Product Type Native Protein
Size US$3605Purchase it in Cusabio online store
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Relevance Lactoferrin is a glycoprotein present in most human mucosal secretions, including human milk. Lactoferrin is bacteriostatic in low iron media and, in some settings, bactericidal. Lactoferrin impairs ability of Shigella flexneri serotype 5 strain M90T to invade HeLa cells. To determine the mechanism by which lactoferrin decreases invasiveness of Shigella organisms, its effect on the major virulence proteins responsible for bacterial uptake by host cells was evaluated. Lactoferrin induced degradation of invasion plasmid antigens IpaB and, to a lesser extent, IpaC, the key proteins responsible for bacteria-directed phagocytosis by mammalian cells.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Tested Applications ELISA, WB, SDS-PAGE
Form Liquid
Storage Buffer PBS, pH 7.4
Alias N/A
Biological_Activity Not test
Purity >95% (SDS-PAGE)
Sequence Full length protein
Research Area Cardiovascular
Source Purified from Human milk
Protein Names Human Lactoferrin
Storage Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
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