Recombinant Human Trefoil factor 1 protein(TFF1) (Active)

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Code CSB-AP000341HU
Product Type Other
Size US$112Purchase it in Cusabio online store
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Uniprot No. P04155
Lead Time 5-10 business days
Storage Buffer 0.2 μm filtered 20 mM PB, pH 7.4, 150mM NaCl ,lyophilized
Alias Breast cancer estrogen-inducible protein, Polypeptide P1.A, hP1.A, Protein pS2
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human MCF-7 cells is less than 10 μg/ml, corresponding to a specific activity of >100 IU/mg.
Purity >97% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Research Area Signal Transduction
Source E.coli
Gene Names TFF1
Expression Region 25-84aa
Tag Info Tag-Free
Mol. Weight 6.7 kDa
Protein Description Full Length of Mature Protein
PubMed ID 6324130; 3838275; 3822834; 2311759; 2185238; 10950923; 10830953; 15489334; 3146413; 15924415; 16308573; 3261981; 15340161; 3041593; 16718800; 17143957; 17242463; 8521850; 9096235; 10982763; 16697734
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Function Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.
Subcellular Location Secreted
Tissue Specificity Found in stomach, with highest levels in the upper gastric mucosal cells (at protein level). Detected in goblet cells of the small and large intestine and rectum, small submucosal glands in the esophagus, mucous acini of the sublingual gland, submucosal g
Database Links

HGNC: 11755

OMIM: 113710

KEGG: hsa:7031

STRING: 9606.ENSP00000291527

UniGene: Hs.162807

Pathway Estrogen signaling pathway

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