Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ABCA5 Polyclonal antibody

Uniprot No.

Q8WWZ7

Target Names

ABCA5

Alternative Names

ABC13 antibody; ABCA5 antibody; ABCA5_HUMAN antibody; ATP binding cassette sub family A (ABC1) member 5 antibody; ATP binding cassette A5 antibody; ATP binding cassette sub family A member 5 antibody; ATP-binding cassette sub-family A member 5 antibody; DKFZp451F117 antibody; DKFZp779N2435 antibody; EST90625 antibody; FLJ16381 antibody; KIAA1888 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human ATP-binding cassette sub-family A member 5 protein (1230-1355AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Function	May play a role in the processing of autolysosomes.
Gene References into Functions	This report represents the first extensive expression and functional study of ABCA5 in the human brain and our data suggest a plausible function of ABCA5 in the brain as a cholesterol transporter associated with Abeta generation PMID: 25125465 our findings support ABCA5 as a gene underlying the congenital generalized hypertrichosis terminalis phenotype and suggest a novel, previously unrecognized role for this gene in regulating hair growth. PMID: 24831815 The expression of ABCA5 was significantly elevated in parkinson disease brains compared to age- and gender-matched control brains. PMID: 23939407 The ABCB5 gene may be related to the properties of chemoresistance and aggressiveness of melanoma PMID: 20487690 Cloning of ABCA5 and detection of a splice variant. PMID: 12504089 ABCA5 may have a role in prostatic intraepithelial neoplasia PMID: 17289887 There is a correlation of induction of ABCA5 and mRNA with differentiation of colonic neoplasms. PMID: 17541169 Show More Hide All
Subcellular Location	Lysosome membrane, Multi-pass membrane protein, Late endosome membrane, Multi-pass membrane protein, Golgi apparatus membrane, Multi-pass membrane protein
Protein Families	ABC transporter superfamily, ABCA family
Tissue Specificity	Ubiquitously expressed. Highly expressed in testis, skeletal muscle, kidney, liver and placenta.
Database Links	HGNC: 35 OMIM: 612503 KEGG: hsa:23461 STRING: 9606.ENSP00000376443 UniGene: Hs.731824

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Check Code：

Code	CSB-PA845163LA01HU
Size	US$299Purchase it in Cusabio online store (only available for customers from the US)
Image	Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA845163LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA845163LA01HU at dilution of 1:100
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ABCA5 Antibody

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