ABCA5 Antibody

Code CSB-PA845163LA01HU
Size US$299 How to order?
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  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA845163LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA845163LA01HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) ABCA5 Polyclonal antibody
Uniprot No. Q8WWZ7
Target Names ABCA5
Alternative Names ABC13 antibody; ABCA5 antibody; ABCA5_HUMAN antibody; ATP binding cassette sub family A (ABC1) member 5 antibody; ATP binding cassette A5 antibody; ATP binding cassette sub family A member 5 antibody; ATP-binding cassette sub-family A member 5 antibody; DKFZp451F117 antibody; DKFZp779N2435 antibody; EST90625 antibody; FLJ16381 antibody; KIAA1888 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human ATP-binding cassette sub-family A member 5 protein (1230-1355AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated

The ABCA5 Antibody (Product code: CSB-PA845163LA01HU) is Non-conjugated. For ABCA5 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA845163LB01HU ABCA5 Antibody, HRP conjugated ELISA
FITC CSB-PA845163LC01HU ABCA5 Antibody, FITC conjugated
Biotin CSB-PA845163LD01HU ABCA5 Antibody, Biotin conjugated ELISA
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Cholesterol efflux transporter in macrophages that is responsible for APOAI/high-density lipoproteins (HDL) formation at the plasma membrane under high cholesterol levels and participates in reverse cholesterol transport. May play a role in the processing of autolysosomes.
Gene References into Functions
  1. This report represents the first extensive expression and functional study of ABCA5 in the human brain and our data suggest a plausible function of ABCA5 in the brain as a cholesterol transporter associated with Abeta generation PMID: 25125465
  2. our findings support ABCA5 as a gene underlying the congenital generalized hypertrichosis terminalis phenotype and suggest a novel, previously unrecognized role for this gene in regulating hair growth. PMID: 24831815
  3. The expression of ABCA5 was significantly elevated in parkinson disease brains compared to age- and gender-matched control brains. PMID: 23939407
  4. The ABCB5 gene may be related to the properties of chemoresistance and aggressiveness of melanoma PMID: 20487690
  5. Cloning of ABCA5 and detection of a splice variant. PMID: 12504089
  6. ABCA5 may have a role in prostatic intraepithelial neoplasia PMID: 17289887
  7. There is a correlation of induction of ABCA5 and mRNA with differentiation of colonic neoplasms. PMID: 17541169

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Subcellular Location Golgi apparatus membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Cell membrane.
Protein Families ABC transporter superfamily, ABCA family
Tissue Specificity Ubiquitously expressed. Highly expressed in testis, skeletal muscle, kidney, liver and placenta. Expressed in both the epithelial and mesenchymal compartments, present within the outer root sheath (ORS) of the hair follicle as well as dermal sheath. Expre
Database Links

HGNC: 35

OMIM: 612503

KEGG: hsa:23461

STRING: 9606.ENSP00000376443

UniGene: Hs.731824

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