ABCB9 Antibody

Code CSB-PA889064LA01HU
Size US$299 How to order?
  • Western Blot
    Positive WB detected in: HL60 whole cell lysate, Mouse brain tissue, Mouse heart tissue, Mouse kidney tissue
    All lanes: ABCB9 antibody at 5µg/ml
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 85, 80, 67, 76, 78 kDa
    Observed band size: 85 kDa

  • Immunofluorescent analysis of HepG2 cells using CSB-PA889064LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) ABCB9 Polyclonal antibody
Uniprot No. Q9NP78
Target Names ABCB9
Alternative Names ABCB9 antibody; KIAA1520ATP-binding cassette sub-family B member 9 antibody; ATP-binding cassette transporter 9 antibody; ABC transporter 9 protein antibody; hABCB9 antibody; TAP-like protein antibody; TAPL antibody
Raised in Rabbit
Species Reactivity Human, Mouse
Immunogen Recombinant Human ATP-binding cassette sub-family B member 9 protein (630-766AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated

The ABCB9 Antibody (Product code: CSB-PA889064LA01HU) is Non-conjugated. For ABCB9 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA889064LB01HU ABCB9 Antibody, HRP conjugated ELISA
FITC CSB-PA889064LC01HU ABCB9 Antibody, FITC conjugated
Biotin CSB-PA889064LD01HU ABCB9 Antibody, Biotin conjugated ELISA
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA, WB, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IF 1:50-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen for degradation. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Binds and transports smaller and larger peptides with the same affinity. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored.
Gene References into Functions
  1. The structure of the unique domain of TAPL, is reported. PMID: 24013930
  2. LAMP proteins retain TAPL on the limiting membrane of endosomes and prevent its sorting to intraluminal vesicles. PMID: 22641697
  3. These results suggest that TAPL may be localized to the microdomains (lipid rafts) of lysosomal membranes enriched in cholesterol. PMID: 21212514
  4. By dissecting ABCB9, distinct functions were assigned to the core complex and the extra N-terminal transmembrane domain. PMID: 20377823
  5. is part of the peptide-loading complex in the classic route of antigen processing via major histocompatibility complex class I molecules PMID: 15863492
  6. These findings suggest that the transport activity of hTAPL is important for conferring high valinomycin-sensitive phenotype to yeast. PMID: 16554024
  7. the TAPL-specific translocation of peptides into isolated lysosomes strictly requires ATP hydrolysis PMID: 17977821
  8. The ATP-binding of TAPL required Mg(2+), and was observed at neutral pH. Chemical cross-linking experiments suggested that TAPL forms a homodimer in the membrane and under the solubilized conditions. PMID: 18175933
  9. analysis of lipid activation of the lysosomal transport complex ABCB9 PMID: 18434309
  10. These results suggest that the sorting signal for lysosomes is present within the amino-terminal transmembrane domain (Met(1)-Arg(141)) of the TAPL molecule. PMID: 18952056

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Subcellular Location Lysosome membrane; Multi-pass membrane protein.
Protein Families ABC transporter superfamily, ABCB family, MHC peptide exporter (TC 3.A.1.209) subfamily
Tissue Specificity Highly expressed in testis, and at moderate levels in brain, spinal cord, and thyroid. Not expressed in monocytes but strongly expressed during differentiation of monocytes to dendritic cells and macrophages.
Database Links

HGNC: 50

OMIM: 605453

KEGG: hsa:23457

STRING: 9606.ENSP00000280560

UniGene: Hs.511951

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