ACAD8 Antibody

Datasheet

Citations (1)

Code	CSB-PA892457LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: Mouse liver tissue, Mouse heart tissue, Mouse skeletal muscle tissue All lanes: ACAD8 antibody at 3μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 46, 32, 39 kDa Observed band size: 46, 39 kDa Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA892457LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ACAD8 Polyclonal antibody

Uniprot No.

Q9UKU7

Target Names

ACAD8

Alternative Names

ACAD 8 antibody; ACAD-8 antibody; ACAD8 antibody; ACAD8_HUMAN antibody; Activator-recruited cofactor 42 kDa component antibody; Acyl CoA dehydrogenase family member 8 antibody; Acyl Coenzyme A dehydrogenase family member 8 antibody; Acyl-CoA dehydrogenase family member 8 antibody; ARC42 antibody; FLJ22590 antibody; IBD antibody; Isobutyryl-CoA dehydrogenase antibody; Isobutyryl-CoA dehydrogenase; mitochondrial antibody; mitochondrial antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Isobutyryl-CoA dehydrogenase, mitochondrial protein (201-415AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ACAD8 Antibody (Product code: CSB-PA892457LA01HU) is Non-conjugated. For ACAD8 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA892457LB01HU	ACAD8 Antibody, HRP conjugated	ELISA
FITC	CSB-PA892457LC01HU	ACAD8 Antibody, FITC conjugated
Biotin	CSB-PA892457LD01HU	ACAD8 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

Cuproptosis-related gene ACAD8 inhibits the metastatic ability of colorectal cancer by inducing cuproptosis HE Zhuang, Y Chen, S Huang,Frontiers in Immunology,2025

Customer Reviews and Q&A

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Target Background

Function

Isobutyryl-CoA dehydrogenase which catalyzes one of the steps of the valine catabolic pathway. To a lesser extent, is also able to catalyze the oxidation of (2S)-2-methylbutanoyl-CoA.

Gene References into Functions

we discovered a novel c.1156_1158delCAG mutation in ACAD8 in patients with isobutyryl-CoA dehydrogenase deficiency , and investigated the mutation spectrum of ACAD8. PMID: 24635911
first enzymatic and molecular confirmation of a deficiency of this enzyme in a patient PMID: 12359132

Involvement in disease

Isobutyryl-CoA dehydrogenase deficiency (IBDD)

Subcellular Location

Mitochondrion.

Protein Families

Acyl-CoA dehydrogenase family

Tissue Specificity

Detected at comparable levels in all tissues examined (heart, lung, brain, skeletal muscle, pancreas and placenta). Weakly expressed in liver and kidney.

Database Links

HGNC: 87

OMIM: 604773

KEGG: hsa:27034

STRING: 9606.ENSP00000281182

UniGene: Hs.14791

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Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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