ACAP2 Antibody

Code CSB-PA001132GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
ACAP2
Alternative Names
ACAP 2 antibody; ACAP2 antibody; ACAP2_HUMAN antibody; ANK repeat and PH domain-containing protein 2 antibody; Arf GAP with coiled coil ANK repeat and PH domain containing protein 2 antibody; Arf GAP with coiled coil ANK repeat and PH domains 2 antibody; Arf-GAP with coiled-coil antibody; ArfGAP with coiled coil ankyrin repeat and PH domains 2 antibody; CENT B 2 antibody; Centaurin beta2 antibody; Centaurin-beta-2 antibody; CENTB 2 antibody; CENTB2 antibody; Cnt b2 antibody; Cnt-b2 antibody; Cntb2 antibody; KIAA0041 antibody; Similar to yeast ZINC FINGER PROTEIN GCS1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human ACAP2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6).
Gene References into Functions
  1. The down-regulation of circRNA-ACAP2 promoted miR-21-5p expression, which further suppressed the transcription and translation of Tiam1. PMID: 30212824
  2. ACAP2 is a functional homolog of C. elegans CNT-1 and its inactivation or downregulation in human cells may contribute to cancer development PMID: 25853217
  3. ACAP2 has robust, constitutive Arf6 GAP activity in vivo, with little activity toward Arf1. PMID: 18003747
  4. Centaurin beta2/KIAA0041, is a member of the centaurin family of ADP-ribosylation factor directed GTPase-activating proteins. Binding of phosphoinositides to a pleckstrin homology domain may regulate subcellular localisation and activity. PMID: 11050434
Subcellular Location
Endosome membrane; Peripheral membrane protein.
Tissue Specificity
Widely expressed. Highest level in lung.
Database Links

HGNC: 16469

OMIM: 607766

KEGG: hsa:23527

STRING: 9606.ENSP00000324287

UniGene: Hs.593373

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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