ACAT2 Antibody

Code CSB-PA861152ESR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA861152ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ACAT2 Polyclonal antibody
Uniprot No.
Target Names
ACAT2
Alternative Names
Acat2 antibody; acetoacetyl CoA thiolase antibody; acetoacetyl Coenzyme A thiolase antibody; Acetyl CoA acetyltransferase antibody; Acetyl CoA transferase like protein antibody; acetyl Coenzyme A acetyltransferase 2 antibody; Acetyl-CoA acetyltransferase antibody; Acetyl-CoA transferase-like protein antibody; Acyl Coenzyme A cholesterol acyltransferase 2 antibody; Cytosolic acetoacetyl-CoA thiolase antibody; cytosolic antibody; SOAT2 antibody; THIC_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Acetyl-CoA acetyltransferase, cytosolic protein (1-97AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in the biosynthetic pathway of cholesterol.
Gene References into Functions
  1. results demonstrate that the low-level expression of human ACAT2 gene with specific CpG-hypomethylated promoter is regulated by the C/EBP transcription factors in monocytic cells, and imply that the lowly expressed ACAT2 catalyzes the synthesis of certain CE/SE that are assembled into lipoproteins for the secretion PMID: 27688151
  2. Results show that DLAT and ACAT2 as upstream acetyltransferases of K76 and K294 in 6PGD protein. PMID: 25042803
  3. Reduced ACAT2 is associated with impaired butyrate oxidation in ulcerative colitis. PMID: 21987487
  4. Data describe the high resolution structure of human cytosolic acetoacetyl-CoA thiolase (CT), both unliganded (at 2.3 angstroms resolution) and in complex with CoA (at 1.6 angstroms resolution). PMID: 15733928
  5. The increased NPC1L1 and ACAT2 mRNA levels in gallstone patients might indicate an upregulated absorption and esterification of cholesterol in the small intestine. PMID: 19071091

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Subcellular Location
Cytoplasm, cytosol.
Protein Families
Thiolase family
Database Links

HGNC: 94

OMIM: 100678

KEGG: hsa:39

STRING: 9606.ENSP00000356015

UniGene: Hs.571037

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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