ACAT2 Antibody

Code CSB-PA001135GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
ACAT2
Alternative Names
Acat2 antibody; acetoacetyl CoA thiolase antibody; acetoacetyl Coenzyme A thiolase antibody; Acetyl CoA acetyltransferase antibody; Acetyl CoA transferase like protein antibody; acetyl Coenzyme A acetyltransferase 2 antibody; Acetyl-CoA acetyltransferase antibody; Acetyl-CoA transferase-like protein antibody; Acyl Coenzyme A cholesterol acyltransferase 2 antibody; Cytosolic acetoacetyl-CoA thiolase antibody; cytosolic antibody; SOAT2 antibody; THIC_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human ACAT2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in the biosynthetic pathway of cholesterol.
Gene References into Functions
  1. results demonstrate that the low-level expression of human ACAT2 gene with specific CpG-hypomethylated promoter is regulated by the C/EBP transcription factors in monocytic cells, and imply that the lowly expressed ACAT2 catalyzes the synthesis of certain CE/SE that are assembled into lipoproteins for the secretion PMID: 27688151
  2. Results show that DLAT and ACAT2 as upstream acetyltransferases of K76 and K294 in 6PGD protein. PMID: 25042803
  3. Reduced ACAT2 is associated with impaired butyrate oxidation in ulcerative colitis. PMID: 21987487
  4. Data describe the high resolution structure of human cytosolic acetoacetyl-CoA thiolase (CT), both unliganded (at 2.3 angstroms resolution) and in complex with CoA (at 1.6 angstroms resolution). PMID: 15733928
  5. The increased NPC1L1 and ACAT2 mRNA levels in gallstone patients might indicate an upregulated absorption and esterification of cholesterol in the small intestine. PMID: 19071091

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Subcellular Location
Cytoplasm, cytosol.
Protein Families
Thiolase family
Database Links

HGNC: 94

OMIM: 100678

KEGG: hsa:39

STRING: 9606.ENSP00000356015

UniGene: Hs.571037

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