ACBD5 Antibody

Code CSB-PA725893HA01HU
Size US$166
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Image
  • Western blot
    All lanes: ACBD5 antibody at 2µg/ml + Hela whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 61, 55, 59, 47 kDa
    Observed band size: 61 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ACBD5 Polyclonal antibody
Uniprot No.
Target Names
ACBD5
Alternative Names
Acbd5 antibody; ACBD5_HUMAN antibody; Acyl CoA binding domain containing 5 antibody; Acyl CoA binding domain containing protein 5 antibody; Acyl Coenzyme A binding domain containing 5 antibody; Acyl-CoA-binding domain-containing protein 5 antibody; DKFZp434A2417 antibody; Endozepine related protein antibody; KIAA1996 antibody; Membrane associated diazepam binding inhibitor antibody; OTTHUMP00000019362 antibody; OTTHUMP00000019363 antibody; OTTHUMP00000019364 antibody; OTTHUMP00000019365 antibody; RP11-85G18.5 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Acyl-CoA-binding domain-containing protein 5 protein (1-461AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ACBD5 Antibody (Product code: CSB-PA725893HA01HU) is Non-conjugated. For ACBD5 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA725893HB01HU ACBD5 Antibody, HRP conjugated ELISA
FITC CSB-PA725893HC01HU ACBD5 Antibody, FITC conjugated
Biotin CSB-PA725893HD01HU ACBD5 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function
Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
Gene References into Functions
  1. ACBD5 captures VLC-CoAs on the cytosolic side of the peroxisomal membrane so that the transport of VLC-CoAs into peroxisomes and subsequent beta-oxidation thereof can proceed efficiently. PMID: 27899449
  2. ACBD5-VAPB interaction regulates peroxisome-endoplasmic reticulum associations. Loss of PO-ER association perturbs PO membrane expansion and increases PO movement. PMID: 28108524
  3. VAP-ACBD5-mediated contact between the endoplasmic reticulum and peroxisomes mediate organelle maintenance and lipid homeostasis. PMID: 28108526
  4. Findings suggest that the ACBD5-RET rearrangement is causatively involved in the development of papillary thyroid cancer. PMID: 25175022
  5. Yeast Atg37, which is homologous to human ACBD5, is involved in autophagy of peroxisomes. PMID: 24905344
  6. A mutation in the acyl-coenzyme A binding domain-containing protein 5 gene (ACBD5 ) may have a role in autosomal dominant thrombocytopenia PMID: 20626622

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Subcellular Location
Peroxisome membrane; Single-pass membrane protein.
Protein Families
ATG37 family
Database Links

HGNC: 23338

OMIM: 616618

KEGG: hsa:91452

STRING: 9606.ENSP00000379568

UniGene: Hs.530597

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