ADAMTS12 Antibody

1. ADAMTS 1, 4, 12, and 13 levels in the maternal and cord blood were lower in the preeclampsia group than in the control group. ADAMTS 1, 4, and 12 levels in placental tissues were higher in the preeclampsia group. PMID: 29135310
2. ADAMTS12 expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
3. Decreased levels of ADAMTS-12 were found to be associated with intrahepatic cholestasis of pregnancy. PMID: 26363034
4. ADAMTS-12 is a multifaced metalloproteinase in arthritis and inflammation [review] PMID: 24876675
5. ADAMTS-12 is implicated in the inflammatory response by modulating normal neutrophil apoptosis. PMID: 23019333
6. Our results suggest that ADAMTS12 may be a susceptibility gene for RA development. PMID: 22505177
7. statistically significant increase in mRNA expression of ADAMTS-7 and ADAMTS-12 was observed in the endplate cells in degenerative discs compared with nondegenerative discs PMID: 22247065
8. The data supported the hypothesis that genetic variations in ADAMTS12 influence the risk of schizophrenia. PMID: 22322903
9. expression of ADAMTS12 in colorectal cancer stroma plays an important role in inhibiting tumor development PMID: 21559743
10. This study identifies a novel biological role for ADAMTS-12, and highlights the importance and complexity of its non-proteolytic domain(s) pertaining to its function. PMID: 21494557
11. ADAMTS-12 is a new COMP-interacting and -degrading enzyme and thus may play an important role in the COMP degradation in the initiation and progression of arthritis PMID: 16611630
12. data suggest that ADAMTS12 confers tumour-protective functions upon cells that produce this proteolytic enzyme PMID: 17895370
13. ADAMTS-7 and ADAMTS-12 are newly identified enzymes responsible for cartilage oligomeric matrix protein degradation in arthritis. PMID: 19098927
14. Results demonstrate that ADAMTS-12, a downstream molecule of PTHrP signaling, is a novel regulator of chondrogenesis. PMID: 19151918
15. ADAMTS-12 is a novel anti-tumor protease that can reduce the proliferative properties of tumor cells. PMID: 19638407

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HGNC: 14605

OMIM: 606184

KEGG: hsa:81792

STRING: 9606.ENSP00000422554

UniGene: Hs.12680