ADPGK Antibody

Code CSB-PA001380GA01HU
Size US$685
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Product Details

Uniprot No. Q9BRR6
Target Names ADPGK
Alternative Names 2610017G09Rik antibody; ADP dependent glucokinase antibody; ADP GK antibody; ADP-dependent glucokinase antibody; ADP-GK antibody; ADPGK antibody; ADPGK_HUMAN antibody; ATP dependent glucokinase antibody; DKFZP434B195 antibody; RbBP 35 antibody; RbBP-35 antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Human ADPGK
Immunogen Species Homo sapiens (Human)
Isotype IgG
Purification Method Antigen Affinity purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications ELISA,WB,IHC
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity).
Gene References into Functions
  1. ADPGK is substrate inhibited by high glucose concentration and shows high specificity for glucose, with no activity for other sugars, as determined by NMR spectroscopy, including 2-deoxyglucose PMID: 26555263
  2. ADPGK can contribute to tumour cell survival under conditions of high glycolytic dependence. PMID: 23799003
  3. human ADPGK(ADP-dependent glucokinase) catalyses ADP-dependent phosphorylation of glucose in vitro, but despite its high expression in human tumour cell lines it appears not to make a quantifiable contribution to glycolysis under the conditions evaluated. PMID: 22219026
  4. Glucose and insulin response to oral glucose is higher in GCK(261) carriers, indicating clinical heterogeneity in GCK maturity diabetes carriers. PMID: 19903754
  5. The presence of mild persistent hyperglycemia in any patient without autoantibodies should lead to genetic analysis of glucokinase, particularly if there is a positive family history. PMID: 19309449

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Subcellular Location Secreted
Protein Families ADP-dependent glucokinase family
Database Links

HGNC: 25250

OMIM: 611861

KEGG: hsa:83440

STRING: 9606.ENSP00000312250

UniGene: Hs.562587

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