ADSS Antibody

Code CSB-PA001398GA01HU
Size US$685 How to order?
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Product Details

Uniprot No. P30520
Target Names ADSS
Alternative Names ADSS2 antibody; ADSS antibody; Adenylosuccinate synthetase isozyme 2 antibody; AMPSase 2 antibody; AdSS 2 antibody; EC antibody; Adenylosuccinate synthetase antibody; acidic isozyme antibody; Adenylosuccinate synthetase antibody; liver isozyme antibody; L-type adenylosuccinate synthetase antibody; IMP--aspartate ligase 2 antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Human ADSS
Immunogen Species Homo sapiens (Human)
Isotype IgG
Purification Method Antigen Affinity purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications ELISA,WB
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
Gene References into Functions
  1. Kinetic data reveal that human Ser(289) and B. subtilis Ser(262) and Ser(263) are essential for catalysis, while the ability of these Ser mutants to bind APBADP suggests that they do not contribute to substrate affinity PMID: 18469177
  2. These findings suggest that the combined effects of the polymorphisms in the ADSS and ATM genes may confer susceptibility to the development of schizophrenia in a Chinese population PMID: 19115993
Subcellular Location Cytoplasm. Mitochondrion. Note=Partially associated with particulate fractions.
Protein Families Adenylosuccinate synthetase family
Database Links

HGNC: 292

OMIM: 103060

KEGG: hsa:159

STRING: 9606.ENSP00000355493

UniGene: Hs.498313

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