ADSS Antibody

Datasheet

Code	CSB-PA001398GA01HU
Size	US$685
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Product Details

Uniprot No.	P30520
Target Names	ADSS
Alternative Names	ADSS2 antibody; ADSS antibody; Adenylosuccinate synthetase isozyme 2 antibody; AMPSase 2 antibody; AdSS 2 antibody; EC 6.3.4.4 antibody; Adenylosuccinate synthetase antibody; acidic isozyme antibody; Adenylosuccinate synthetase antibody; liver isozyme antibody; L-type adenylosuccinate synthetase antibody; IMP--aspartate ligase 2 antibody
Raised in	Rabbit
Species Reactivity	Human,Mouse,Rat
Immunogen	Human ADSS
Immunogen Species	Homo sapiens (Human)
Isotype	IgG
Purification Method	Antigen Affinity purified
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications	ELISA,WB
Protocols	ELISA Protocol Western Blotting(WB) Protocol
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time	Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Function	Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
Gene References into Functions	Kinetic data reveal that human Ser(289) and B. subtilis Ser(262) and Ser(263) are essential for catalysis, while the ability of these Ser mutants to bind APBADP suggests that they do not contribute to substrate affinity PMID: 18469177 These findings suggest that the combined effects of the polymorphisms in the ADSS and ATM genes may confer susceptibility to the development of schizophrenia in a Chinese population PMID: 19115993
Subcellular Location	Cytoplasm
Protein Families	Adenylosuccinate synthetase family
Database Links	HGNC: 292 OMIM: 103060 KEGG: hsa:159 STRING: 9606.ENSP00000355493 UniGene: Hs.498313

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