AFTPH Antibody

Datasheet

Code	CSB-PA001422LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA001422LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) AFTPH Polyclonal antibody

Uniprot No.

Q6ULP2

Target Names

AFTPH

Alternative Names

AFTIN_HUMAN antibody; Aftiphilin antibody; Aftiphilin protein antibody; Aftph antibody; MGC33965 antibody; Nbla10388 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Aftiphilin protein (752-889AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The AFTPH Antibody (Product code: CSB-PA001422LA01HU) is Non-conjugated. For AFTPH Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA001422LB01HU	AFTPH Antibody, HRP conjugated	ELISA
FITC	CSB-PA001422LC01HU	AFTPH Antibody, FITC conjugated
Biotin	CSB-PA001422LD01HU	AFTPH Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Component of clathrin-coated vesicles. Component of the aftiphilin/p200/gamma-synergin complex, which plays roles in AP1G1/AP-1-mediated protein trafficking including the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes.

Gene References into Functions

the aftiphilin/p200/gamma-synergin complex facilitates AP-1 function PMID: 15758025
Data show that by recruiting aftiphilin/gamma-synergin in addition to clathrin, AP-1 coordinates formation of Weibel-Palade bodies with their acquisition of a regulated secretory phenotype. PMID: 18815278

Subcellular Location

Cytoplasm. Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle.

Database Links

HGNC: 25951

STRING: 9606.ENSP00000238855

UniGene: Hs.655167

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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