AGBL2 Antibody

Datasheet

Code	CSB-PA732978LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA732978LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA732978LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) AGBL2 Polyclonal antibody

Uniprot No.

Q5U5Z8

Target Names

AGBL2

Alternative Names

AGBL 2 antibody; AGBL2 antibody; ATP/GTP binding protein like 2 antibody; ATP/GTP-binding protein-like 2 antibody; Carboxypeptidase 2 cytosolic antibody; CBPC2_HUMAN antibody; CCP2 antibody; Cytosolic carboxypeptidase 2 antibody; FLJ23598 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Cytosolic carboxypeptidase 2 protein (10-270AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The AGBL2 Antibody (Product code: CSB-PA732978LA01HU) is Non-conjugated. For AGBL2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA732978LB01HU	AGBL2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA732978LC01HU	AGBL2 Antibody, FITC conjugated
Biotin	CSB-PA732978LD01HU	AGBL2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK.

Gene References into Functions

Findings suggest that ATP/GTP binding protein like 2 (AGBL2) plays a critical oncogenic role in the pathogenesis of hepatocellular carcinoma (HCC) through modulation on immunity-related GTPase family, M protein (IRGM)-regulated autophagy and aurora kinase A (Aurora A) activity. PMID: 29126912
Suggest role for AGBL2 in cell proliferation and chemotherapy resistance in gastric cancer. PMID: 25916089
High AGBL2 expression is associated with breast cancer. PMID: 24884516
RARRES1, its interacting partners AGBL2, Eg5/KIF11, another EEY-bearing protein (EB1), and the microtubule tyrosination cycle are important in tumorigenesis. PMID: 21303978

Subcellular Location

Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body.

Protein Families

Peptidase M14 family

Database Links

HGNC: 26296

OMIM: 617345

KEGG: hsa:79841

STRING: 9606.ENSP00000298861

UniGene: Hs.147377

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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