AGO4 Antibody

Code CSB-PA950500
Size US$299
Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA950500(AGO4 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No. Q9HCK5
Target Names AGO4
Alternative Names AGO4_HUMAN antibody; Argonaute4 antibody; eIF-2C 4 antibody; eIF2C 4 antibody; eif2c4 antibody; Eukaryotic translation initiation factor 2C 4 antibody; hAgo4 antibody; Protein argonaute-4 antibody
Raised in Rabbit
Species Reactivity Human,Mouse
Immunogen Synthetic peptide of Human AGO4
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Isotype IgG
Purification Method Antigen affinity purification
Concentration It differs from different batches. Please contact us to confirm it.
Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form Liquid
Tested Applications ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
IHC 1:25-1:100
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV).
Gene References into Functions
  1. Chimeras with Ago4 N-terminal domains were defective in RISC activation & sometimes also in RNA loading. This highlights the pleiotropic role of the Ago N domain & emphasizes the unique position of human Ago4 within the Ago protein family. PMID: 23748378
  2. EIF2C4 protein is expressed in differentiating and terminally differentiated N-type cells more than in S- and I-type cells PMID: 19393748
Subcellular Location Cytoplasm, P-body
Protein Families Argonaute family, Ago subfamily
Database Links

HGNC: 18424

OMIM: 607356

KEGG: hsa:192670

STRING: 9606.ENSP00000362306

UniGene: Hs.744858

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