AGO4 Antibody

Code CSB-PA977504
Size US$166
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  • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Raji cells, 293T cells, PC3 cells, Primary antibody: CSB-PA977504(AGO4 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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Product Details

Uniprot No.
Target Names
AGO4
Alternative Names
AGO4_HUMAN antibody; Argonaute4 antibody; eIF-2C 4 antibody; eIF2C 4 antibody; eif2c4 antibody; Eukaryotic translation initiation factor 2C 4 antibody; hAgo4 antibody; Protein argonaute-4 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide of Human AGO4
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
WB 1:500-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV).
Gene References into Functions
  1. Chimeras with Ago4 N-terminal domains were defective in RISC activation & sometimes also in RNA loading. This highlights the pleiotropic role of the Ago N domain & emphasizes the unique position of human Ago4 within the Ago protein family. PMID: 23748378
  2. EIF2C4 protein is expressed in differentiating and terminally differentiated N-type cells more than in S- and I-type cells PMID: 19393748
Subcellular Location
Cytoplasm, P-body.
Protein Families
Argonaute family, Ago subfamily
Database Links

HGNC: 18424

OMIM: 607356

KEGG: hsa:192670

STRING: 9606.ENSP00000362306

UniGene: Hs.744858

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