AGTPBP1 Antibody

Datasheet

Code	CSB-PA001464GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9UPW5

Target Names

AGTPBP1

Alternative Names

CCP1 antibody; 1700020N17Rik antibody; 2310001G17Rik antibody; 2900054O13Rik antibody; 4930445M19Rik antibody; 5730402G09Rik antibody; AGTPBP 1 antibody; AGTPBP1 antibody; ATP/GTP binding protein 1 antibody; ATP/GTP-binding protein 1 antibody; BB114605 antibody; Carboxypeptidase tubulin antibody; CBPC1_HUMAN antibody; Cytosolic carboxypeptidase 1 antibody; DKFZp686M20191 antibody; KIAA1035 antibody; MGC90651 antibody; mKIAA1035 antibody; Nervous system nuclear protein induced by axotomy antibody; Nervous system nuclear protein induced by axotomy protein 1 homolog antibody; nmf243 antibody; NNA1 antibody; OTTHUMP00000021581 antibody; OTTHUMP00000063553 antibody; pcd antibody; Purkinje cell degeneration antibody; RP11-30C23.1 antibody; Soluble carboxypeptidase antibody; Tubulinyl Tyr carboxypeptidase antibody; Tyrosine carboxypeptidase antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human AGTPBP1

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Metallocarboxypeptidase that mediates protein deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of alpha-tubulin as well as non-tubulin proteins such as MYLK. Involved in KLF4 deglutamylation which promotes KLF4 proteasome-mediated degradation, thereby negatively regulating cell pluripotency maintenance and embryogenesis.

Gene References into Functions

we identified seven new putative CCP1 substrates, all of them harboring acidic amino acids in their gene-encoded C terminus PMID: 25381060
Data indicate that a functional nuclear export signals (NESs) in CCP1 that mediates direct binding to the export receptor CRM1. PMID: 23242554

Subcellular Location

Cytoplasm. Cytoplasm, cytosol. Nucleus. Mitochondrion.

Protein Families

Peptidase M14 family

Database Links

HGNC: 17258

OMIM: 606830

KEGG: hsa:23287

STRING: 9606.ENSP00000365251

UniGene: Hs.719980

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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