AK6 Antibody

Code CSB-PA000841
Size US$100
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  • Western Blot analysis of Jurkat cells using AK6 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
AK6
Alternative Names
AD-004 antibody; Adenylate kinase isoenzyme 6 antibody; Adrenal gland protein AD-004 antibody; AK/ATPase antibody; AK6 antibody; CGI-137 antibody; CIP antibody; Coilin-interacting nuclear ATPase protein antibody; Dual activity adenylate kinase/ATPase antibody; hCINAP antibody; KAD6_HUMAN antibody; TAF9 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the N-terminal region of Human AK6.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. AMP and dAMP are the preferred substrates, but CMP and dCMP are also good substrates. IMP is phosphorylated to a much lesser extent. All nucleoside triphosphates ATP, GTP, UTP, CTP, dATP, dCTP, dGTP, and TTP are accepted as phosphate donors. CTP is the best phosphate donor, followed by UTP, ATP, GTP and dCTP. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
Gene References into Functions
  1. hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation. PMID: 28516914
  2. purification and X ray crystal structure PMID: 15213396
  3. hCINAP is a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locus PMID: 16079131
Subcellular Location
Nucleus, nucleoplasm. Nucleus, Cajal body. Note=Displays widespread diffuse nucleoplasmic distribution but not detected in nucleoli. Detected in Cajal bodies but not in all cells.
Protein Families
Adenylate kinase family, AK6 subfamily
Tissue Specificity
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, chorionic villi and the central nervous system.
Database Links

HGNC: 49151

KEGG: hsa:102157402

UniGene: Hs.653163

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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