ALG2 Antibody

Code CSB-PA863983ESR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human cervical cancer using CSB-PA863983ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA863983ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ALG2 Polyclonal antibody
Uniprot No.
Target Names
ALG2
Alternative Names
ALG2; UNQ666/PRO1298; Alpha-1,3/1,6-mannosyltransferase ALG2; Asparagine-linked glycosylation protein 2 homolog; GDP-Man:Man(1GlcNAc(2-PP-Dol alpha-1,3-mannosyltransferase; GDP-Man:Man(1GlcNAc(2-PP-dolichol mannosyltransferase; GDP-Man:Man(2GlcNAc(2-PP-Dol alpha-1,6-mannosyltransferase
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Alpha-1,3/1,6-mannosyltransferase ALG2 protein (197-416AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
Gene References into Functions
  1. We identify ALG14 and ALG2 as novel genes in which mutations cause a congenital myasthenic syndrome PMID: 23404334
  2. The ALG2 binding site is necessary for the punctate distribution of the carboxyl-terminal proline-rich region of Alix in HeLa cells. PMID: 14999017
  3. The expression and transport of ALG-2 in association with TSG101 and Vps4B are reported. PMID: 16004603
Involvement in disease
Congenital disorder of glycosylation 1I (CDG1I); Myasthenic syndrome, congenital, 14 (CMS14)
Subcellular Location
Membrane; Single-pass membrane protein.
Protein Families
Glycosyltransferase group 1 family, Glycosyltransferase 4 subfamily
Database Links

HGNC: 23159

OMIM: 607905

KEGG: hsa:85365

STRING: 9606.ENSP00000417764

UniGene: Hs.40919

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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