ALS3 Antibody

Datasheet

Code	CSB-PA6452XA01CZF
Size	US$166
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Image	Western Blot Positive WB detected in: recombinant protein All lanes:ALS3 Antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/20000 dilution Predicted band size: 40 kDa Observed band size: 41 kDa
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) ALS3 Polyclonal antibody

Uniprot No.

Q59L12

Target Names

ALS3

Alternative Names

Agglutinin-like protein 3 (3D9 antigen) (Adhesin 3), ALS3, ALS10 ALS8

Raised in

Rabbit

Species Reactivity

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

Immunogen

Recombinant Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) ALS3 protein (18-330aa)

Immunogen Species

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the biofilm formation and pathogenesis of C.albicans infections. Necessary for C.albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent endocytosis by these cells. During disseminated infection, mediates initial trafficking to the brain and renal cortex and contributes to fungal persistence in the kidneys.

Gene References into Functions

Our findings demonstrate that the Bcr1 pathway functions in vivo to promote biofilm formation, and that Als3-mediated adherence is a fundamental property under Bcr1 control. PMID: 16839200

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall.

Protein Families

ALS family

Database Links

KEGG: cal:CAALFM_CR07070CA

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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