AMT Antibody

Code CSB-PA001684LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: A549 whole cell lysate, Mouse brain tissue
    All lanes: AMT antibody at 3.5µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 44, 38, 40, 42 kDa
    Observed band size: 44 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) AMT Polyclonal antibody
Uniprot No.
Target Names
AMT
Alternative Names
Aminomethyltransferase (glycine cleavage system protein T) antibody; Aminomethyltransferase antibody; AMT antibody; GCE antibody; GCST antibody; GCST_HUMAN antibody; GCVT antibody; Glycine cleavage system T protein antibody; mitochondrial antibody; NKH antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Aminomethyltransferase, mitochondrial protein (180-260AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The AMT Antibody (Product code: CSB-PA001684LA01HU) is Non-conjugated. For AMT Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA001684LB01HU AMT Antibody, HRP conjugated ELISA
FITC CSB-PA001684LC01HU AMT Antibody, FITC conjugated
Biotin CSB-PA001684LD01HU AMT Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
The glycine cleavage system catalyzes the degradation of glycine.
Gene References into Functions
  1. The position and frequency of the breakpoint for CNVs correlated with intron size and presence of Alu elements. Missense mutations, most often recurring, were the most common type of disease-causing mutation in AMT PMID: 27362913
  2. Data indicate no mutation was found in glycine cleavage system protein-H (GCSH) and suggest that mutations in both glycine decarboxylase (GLDC) and aminomethyltransferase (AMT) are the main cause of glycine encephalopathy in Malaysian population. PMID: 25231368
  3. Two unique non-synonymous changes were identified in the AMT gene in patients with neural tube defects. PMID: 22171071
  4. x-ray crystallographic structure of human T-protein of glycine cleavage system PMID: 16051266
Involvement in disease
Non-ketotic hyperglycinemia (NKH)
Subcellular Location
Mitochondrion.
Protein Families
GcvT family
Database Links

HGNC: 473

OMIM: 238310

KEGG: hsa:275

STRING: 9606.ENSP00000273588

UniGene: Hs.102

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