ANGPTL1 Antibody

Code CSB-PA004656
Size US$100
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  • Western Blot analysis of rat stomach rat intestines cells using Angptl1 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
ANGPTL1
Alternative Names
ANG 3 antibody; ANG-3 antibody; ANG3 antibody; Angioarrestin antibody; Angiopoietin 3 antibody; Angiopoietin like 1 antibody; Angiopoietin like protein 1 antibody; Angiopoietin related protein 1 antibody; Angiopoietin Y1 antibody; Angiopoietin-3 antibody; Angiopoietin-like protein 1 antibody; Angiopoietin-related protein 1 antibody; ANGL1_HUMAN antibody; ANGPT3 antibody; ANGPTL1 antibody; AngY antibody; ARP1 antibody; dJ595C2.2 antibody; KIAA0351 antibody; UNQ162 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the N-terminal region of Human Angptl1.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. Low levels of ANGPTL1 is associated with colorectal cancer metastasis. PMID: 28606130
  2. ANGPTL1 inhibited angiogenesis by interacting with integrin alpha1beta1 receptor to suppress the downstreamJAK2-STAT3 signaling pathway. PMID: 28904065
  3. Aberrant expression of ANGPTL1 in cumulus cells is potentially associated with impaired oocyte developmental competence in polycystic ovary syndrome. PMID: 26829602
  4. Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis PMID: 25970467
  5. ANGPTL1 represses lung cancer cell motility by abrogating the expression of the epithelial mesenchymal transformation mediator SLUG. PMID: 23434592
  6. Inhibits experimental melanoma growth when transfected into murine cells. PMID: 15940350
  7. Immunohistochemical staining of Ang-1 was observed in smooth muscle cells, whereas Ang-2 was detected in endothelial cells, smooth muscle cells and macrophages. PMID: 18182823
  8. Overexpression of angiopoietin 1 and metalloproteinases may be the characteristic feature of endometrium with greater potential to transform into endometriotic lesions in the peritoneal cavity. PMID: 18644593

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Subcellular Location
Secreted.
Tissue Specificity
Highly expressed in adrenal gland, placenta, thyroid gland, heart, skeletal muscle and small intestine. Weakly expressed in testis, ovary, colon, pancreas, kidney and stomach.
Database Links

HGNC: 489

OMIM: 603874

KEGG: hsa:9068

STRING: 9606.ENSP00000234816

UniGene: Hs.591474

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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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