AP1S3 Antibody, Biotin conjugated

Code CSB-PA001868ED01HU
Size US$299
  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA001868ED01HU at dilution of 1:100
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Product Details

Full Product Name Rabbit anti-Human AP1S3 Polyclonal antibody
Uniprot No. Q96PC3
Target Names AP1S3
Alternative Names
Adapter-related protein complex 1 subunit sigma-1C antibody; Adaptor protein complex AP 1 sigma 1C subunit antibody; Adaptor protein complex AP-1 subunit sigma-1C antibody; Adaptor related protein complex 1 sigma 3 subunit antibody; AP-1 complex subunit sigma-3 antibody; Ap1s3 antibody; AP1S3_HUMAN antibody; Clathrin assembly protein complex 1 sigma-1C small chain antibody; Golgi adaptor HA1/AP1 adaptin sigma-1C subunit antibody; Sigma 1C subunit of AP-1 clathrin antibody; Sigma-adaptin 1C antibody; Sigma1C-adaptin antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human AP-1 complex subunit sigma-3 protein (1-104AA)
Immunogen Species Human
Conjugate Biotin
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Involved in TLR3 trafficking.
Gene References into Functions
  1. study demonstrated that AP1S3 interacts with hepatitis C virus E2 and protects it from proteasome-dependent degradation PMID: 27079945
  2. AP1S3 silencing disrupted the endosomal translocation of the innate pattern-recognition receptor TLR-3 (Toll-like receptor 3) and resulted in a marked inhibition of downstream signaling. PMID: 24791904
Involvement in disease Psoriasis 15, pustular (PSORS15)
Subcellular Location Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein Families Adaptor complexes small subunit family
Tissue Specificity Widely expressed.
Database Links

HGNC: 18971

OMIM: 615781

KEGG: hsa:130340

STRING: 9606.ENSP00000379891

UniGene: Hs.632555

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