APOBEC3A Antibody

Code CSB-PA001921LA01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) APOBEC3A Polyclonal antibody
Uniprot No.
Target Names
APOBEC3A
Alternative Names
A3A antibody; ABC3A_HUMAN antibody; APOBEC3A antibody; Apolipoprotein B mRNA editing enzyme antibody; Apolipoprotein B mRNA editing enzyme; catalytic polypeptide like 3A antibody; ARP3 antibody; bK150C2.1 antibody; Catalytic polypeptide like 3A antibody; Phorbolin 1 antibody; Phorbolin-1 antibody; PHRBN antibody; Probable DNA dC >dU editing enzyme APOBEC-3A antibody; Probable DNA dC->dU-editing enzyme APOBEC-3A antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human DNA dC->dU-editing enzyme APOBEC-3A protein (1-199AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The APOBEC3A Antibody (Product code: CSB-PA001921LA01HU) is Non-conjugated. For APOBEC3A Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA001921LB01HU APOBEC3A Antibody, HRP conjugated ELISA
FITC CSB-PA001921LC01HU APOBEC3A Antibody, FITC conjugated
Biotin CSB-PA001921LD01HU APOBEC3A Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Gene References into Functions
  1. the APOBEC3A/B deletion polymorphism was not associated with risk of breast, lung, colon or prostate cancer in this Norwegian cohort PMID: 29140415
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
Cytidine and deoxycytidylate deaminase family
Tissue Specificity
Expressed in peripheral leukocytes with higher expression in CD14-positive phagocytic cells. Highly expressed in keratinocytes and in periphery blood monocytes. Also detected in non-lymphoid tissues including lung and adipose tissues. Found at high levels
Database Links

HGNC: 17343

OMIM: 607109

KEGG: hsa:100913187

STRING: 9606.ENSP00000249116

UniGene: Hs.226307

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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