ARF3 Antibody

Code CSB-PA001990ESR1HU
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
Image
  • Western blot
    All lanes: ARF3 antibody at 6μg/ml + Mouse brain tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 21, 17 kDa
    Observed band size: 21 kDa

  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA001990ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA001990ESR1HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) ARF3 Polyclonal antibody
Uniprot No. P61204
Target Names ARF3
Alternative Names ADP ribosylation factor 3 antibody; ADP-ribosylation factor 3 antibody; ARF3 antibody; ARF3_HUMAN antibody; small GTP binding protein antibody
Raised in Rabbit
Species Reactivity Human, Mouse
Immunogen Recombinant Human ADP-ribosylation factor 3 protein (1-181AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form Liquid
Tested Applications ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Gene References into Functions
  1. Upregulation of ARF3 is associated with ovarian cancer. PMID: 28098897
  2. activated ARF3 is associated with Unc93B1 and TLR9, suggesting that ARF3 conducts TLR9 trafficking by forming the TLR9-Unc93B1-ARF3 complex. PMID: 26067373
  3. ARF1+ARF3 are required for integrity of recycling endosomes but are involved in distinct transport pathways: they are required for the transferrin recycling pathway from endosomes to the plasma membrane. PMID: 23783033
  4. These results suggest that Arf3 plays a unique function at the trans-Golgi network that likely involves recruitment by a specific receptor. PMID: 20357002
  5. expression and subcellular redistribution by heregulin PMID: 12135740

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Subcellular Location Golgi apparatus. Cytoplasm, perinuclear region.
Protein Families Small GTPase superfamily, Arf family
Database Links

HGNC: 654

OMIM: 103190

KEGG: hsa:377

STRING: 9606.ENSP00000256682

UniGene: Hs.119177

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